Objective:To determine whether there is difference in the prescribed amount of opioids between Wa and Han Chinese patients with cancer pain.Methods:The data of Wa and Han Chinese patients with cancer pain who visited a hospital from January 2020 to December 2022 were retrospectively collected.The Han Chinese patients with cancer pain were included in the control group(n=232)and the Wa Chinese patients with cancer pain were included in the observation group(n=30).The general data and prescribed amount of opioids were statistically analyzed for the two groups.Results:It was noted that all patients in the two groups had moderate to severe cancer pain,and there was no statistically significant difference in age,sex,body mass index,TNM stage,initial NRS score,tumor type,adjuvant medication or previous opioid treatment between the two groups(P＞0.05).The 24h-prescribed amount of opioids and body weight-24h-prescribed amount of opioids in the observation group were both less than those in the control group(P＜0.05).The body weight-body surface area-24h-prescribed amount of opioids showed no statistically significant difference between the two groups(P＞0.05),but was lower in the observation group as compared with the control group.Conclusion:There are differences in the prescribed amount of opioids between Wa and Han Chinese patients with cancer pain,as demonstrated by less amount prescribed for Wa Chinese patients as compared with the Han Chinese patients.
关键词
癌痛/佤族/汉族/阿片类药物/儿茶酚胺氧位甲基转移酶rs4680基因多态性
Key words
cancer pain/Wa Chinese/Han Chinese/opioids/polymorphism of catechol-O-methyltransferase rs4680 gene
维普
万方数据