A Case Report of Gemcitabine Combined with Oxaliplatin and Toripalimab in the Treatment of Thrombocytopenia Caused by Splenic Metastasis after Surgery for Intrahepatic Cholangiocarcinoma
Intrahepatic cholangiocarcinoma(ICC)is a type of primary liver cancer.This report details a case of splenic metastasis after surgery for ICC in a 63-year-old male patient on maintenance treatment,who was treated with combination therapy with gemcitabine+oxaliplatin+toripalimab and showed decreased white blood cell count and reduced platelet count during the chemotherapy cycle.The patient showed increased white blood cell count and further reduced platelet count in response to treatment with recombinant human granulocyte colony-stimulating factor injection,and showed increased platelet count after symptomatic treatment with recombinant human thrombopoietin injection.For patients with advanced ICC,clinicians may provide appropriate symptomatic treatment according to expert guidelines and consensus,so as to prolong the survival time of patients.