Characteristics and Risk Factors of Pulmonary Infection in Patients with Acute Cerebral Infarction
Objective:To analyze the characteristics and risk factors of pulmonary infection in patients with acute cerebral infarction,so as to provide reference for the prevention and treatment of such diseases.Methods:A total of 122 patients with acute cerebral infarction who visited the department of neurology during January 2019 to January 2021 were retrospectively selected and divided into control group (without pulmonary infection,n=63) and infection group (with pulmonary infection,n=59).Clinical medical records and medications used were collected for the two patient groups to summarize the characteristics of pulmonary infection.The distribution of pathogenic bacteria and drug resistance characteristics of 59 patients in the infection group were analyzed.Logistic regression model was used to analyze related influencing factors of pulmonary infection in patients with acute cerebral infarction.Results:A total of 79 pathogenic bacteria were isolated from the 59 infected patients in the infection group,including 48 strains (60.76％) of Gram-negative bacteria,mainly Klebsiella pneumoniae and Escherichia coli;and 31 strains (39.24％) of Gram-positive bacteria,mainly Staphylococcus aureus.The resistant rates of Klebsiella pneumoniae to cefoxitin,ticarcillin clavulanate potassium,ampicillin sulbactam,amikacin,gentamicin,levofloxacin and cefuroxime were relatively high,all above 80.00％.The resistance rates of Staphylococcus aureus to erythromycin,penicillin G,cefoxitin,levofloxacin and moxifloxacin were relatively high,all above 75.00％.Logistic regression analysis showed that hypoproteinemia,hyponatremia,invasive procedure,consciousness disturbance,white blood cell (WBC),C-reactive protein (CRP) were independent risk factors of acute cerebral infarction complicated with pulmonary infection (P<0.05).Conclusion:Acute cerebral infarction patients with hypoproteinemia,hyponatremia,invasive procedure,consciousness disturbance and elevated levels of WBC and CRP are at increased risk of pulmonary infection.The above factors should be corrected actively,and anti-infection treatment should be carried out according to the common pathogenic bacteria,drug sensitivity and characteristics of antibiotics,and effective preventive and therapeutic measures should be taken to reduce the incidence of pulmonary infection and improve the therapeutic effect.
万方数据
维普
