首页|香菊胶囊联合嗅觉训练对慢性鼻窦炎诱发嗅觉障碍患者术后康复的影响

香菊胶囊联合嗅觉训练对慢性鼻窦炎诱发嗅觉障碍患者术后康复的影响

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目的:探讨香菊胶囊联合嗅觉训练对慢性鼻窦炎诱发嗅觉障碍患者术后康复的影响.方法:选取 2022 年1月~2023 年12 月期间某院收治的134例慢性鼻窦炎诱发嗅觉障碍患者作为研究对象,采用随机数字表法分为对照组和观察组,每组 67 例.对照组患者给予嗅觉训练,观察组患者在对照组治疗基础上给予香菊胶囊辅助治疗.比较两组患者临床疗效、嗜酸性粒细胞百分比(EOS%)、炎症因子[白介素-6(IL-6)、白介素-17(IL-17)和C反应蛋白(CRP)]、疼痛症状[视觉模拟评分(VAS)]及不良反应发生情况.结果:治疗后,观察组患者治疗总有效率(88.06%)高于对照组(74.63%,P<0.05);两组患者EOS%、IL-6、IL-17 和CRP水平均降低,且观察组低于对照组(P<0.05);头痛VAS评分和面部胀痛VAS评分均降低,且观察组低于对照组(P<0.05).治疗期间,观察组患者不良反应总发生率(7.46%)低于对照组(11.94%,P<0.05).结论:香菊胶囊联合嗅觉训练可提高慢性鼻窦炎诱发嗅觉障碍患者的临床疗效,降低炎症反应,减轻疼痛症状,且能减少不良反应的发生.
Effect of Xiangju Capsules Combined with Olfactory Training on Postoperative Rehabilitation of Patients with Dysosmia Induced by Chronic Sinusitis
Objective:To investigate the effect of Xiangju capsules combined with olfactory training on postoperative rehabilitation of patients with dysosmia induced by chronic sinusitis.Methods:A total of 134 patients with dysosmia induced by chronic sinusitis treated in a hospital from January 2022 to December 2023 were selected and assigned to the control group and observation group by random number table method,with 67 patients in each group.The control group was treated with olfactory training,and the observation group was treated with Xiangju capsules in addition to the treatment given in the control group.The clinical efficacy,eosinophil percentage(EOS% ),inflammatory factors[interleukin-6(IL-6),interleukin-17(IL-17)and C-reactive protein(CRP)],pain symptoms[visual analogue scale(VAS)]and adverse reactions were compared between the two groups.Results:After treatment,the total response rate in the observation group(88.06% )was higher than that in the control group(74.63%,P<0.05).The levels of EOS%,IL-6,IL-17 and CRP were decreased in both groups,with the observation group showing lower levels than the control group(P<0.05).Both headache VAS score and facial swelling VAS score were decreased in both groups,with the observation group showing lower levels than the control group(P<0.05).During the treatment period,the total incidence of adverse reactions in the observation group(7.46% )was lower than that in the control group(11.94%,P<0.05).Conclusion:Xiangju capsules combined with olfactory training can improve the clinical treatment effect of patients with dysosmia induced by chronic sinusitis,reducing the inflammatory response,relieving pain symptoms and reducing the incidence of adverse reactions.

Xiangju capsulesolfactory trainingchronic sinusitisdysosmiainflammatory factor

王亚真、王俊杰

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河南省中医院耳鼻喉科,郑州 450002

香菊胶囊 嗅觉训练 慢性鼻窦炎 嗅觉障碍 炎症因子

2024

中国合理用药探索
中国执业药师协会

中国合理用药探索

影响因子:0.62
ISSN:2096-3327
年,卷(期):2024.21(12)