基于"肺与大肠相表里"探析血管内皮细胞与肠道菌群的关联
Exploration on the Relationship between Vascular Endothelial Cells and Intestinal Microbiota Based on the"Exterior-interior Relationship between the Lung and Large Intestine"
安冬 1梁永林 2赵思晨 1赵芸慧 1刘中唐 1裴晓丽1
作者信息
- 1. 甘肃中医药大学,甘肃 兰州 730000
- 2. 甘肃中医药大学,甘肃 兰州 730000;敦煌医学与转化教育部重点实验室,甘肃 兰州 730000
- 折叠
摘要
肠道菌群及其代谢物失调对内皮细胞损伤和功能障碍具有重要影响.中医"肺"与血管内皮细胞在结构、生理及病理方面具有相关性.中医学"肺与大肠相表里"理论是肺与肠在结构、生理及病理方面相关性的高度概括,可作为血管内皮细胞与肠道菌群相关联的理论基础.本文可为以肠道菌群为切入点、修复血管内皮细胞损伤干预心血管疾病的实验研究提供理论依据,并为中医药临床治疗相关疾病提供参考.
Abstract
The imbalance of gut microbiota and its metabolites has a significant impact on endothelial cell damage and dysfunction.There was a correlation between the structure,physiology,and pathology of TCM"lung"and vascular endothelial cells.The theory of"exterior-interior relationship between the lung and large intestine"in TCM is highly summarized correlation between lung and intestine in terms of structure,physiology,and pathology,which can serve as the theoretical basis for the correlation between vascular endothelial cells and intestinal microbiota.This can provide theoretical basis for experimental research on protecting vascular endothelial cell damage and intervening in cardiovascular diseases from the perspective of gut microbiota,as well as reference for clinical treatment of related diseases with TCM.
关键词
内皮细胞/动脉粥样硬化/肠道菌群/肺与大肠相表里Key words
endothelial cells/atherosclerosis/intestinal flora/exterior-interior relationship between the lung and large intestine引用本文复制引用
基金项目
甘肃省高等学校产业支撑计划项目(2021CYZC-03)
甘肃中医药大学研究生创新基金(2022CX05)
出版年
2024
国家科技期刊平台
NSTL
万方数据