首页|2012-2021年人参皂苷研究文献可视化分析

2012-2021年人参皂苷研究文献可视化分析

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目的 对人参皂苷研究文献进行可视化分析,探索人参皂苷的研究热点及前沿.方法 检索中国知识资源总库(CNKI)2012年1月1日-2021年12月31日收录的人参皂苷相关文献,采用VOSviewer1.6.17和CiteSpace5.8.R2软件绘制作者合作视图和关键词共现、聚类、突现及时间线图,并分析.结果 共纳入3 517篇文献,年发文量整体处于平稳波动状态;高频关键词包括"含量测定""细胞凋亡""氧化应激""质量控制""药代动力学""抗氧化""代谢组学""抗肿瘤""肠道菌群""细胞增殖"等;关键词突现分析发现,该领域前期研究聚焦于人参皂苷的提取与含量测定,后期聚焦于作用机制与新药研发.结论 人参皂苷的研究仍处于蓬勃发展态势,其抗炎、抗肿瘤、缓解氧化应激、调节内质网应激等作用机制的研究及针对人参皂苷的新药研发成为该领域的研究热点.
Visualization Analysis on Research Status of Ginsenosides from 2012 to 2021
Objective To conduct bibliometric and visualization analysis on ginsenosides;To preliminarily explore the research hotspot and frontier of ginsenosides.Methods The relevant literature of ginsenosides was retrieved from CNKI from January 1,2012 to December 31,2021.VOSviewer 1.6.17 and CiteSpace 5.8.R2 software were used to draw and analyze the author cooperation view of relevant literature and the co-occurrence,clustering,emergence and time visualization of keywords.Results Totally 3 517 articled were included.The number of publications was stable and fluctuating.High frequency keywords included content determination,apoptosis,oxidative stress,quality control,pharmacokinetics,antioxidant,metabolomics,anti-tumor,intestinal flora,cell proliferation,etc.The emergency analysis showed that the preliminary research in this field focused on the extraction and content determination of ginsenosides,and later focused on the mechanism of action and the development of new drugs.Conclusion The research on ginsenosides is still in a vigorous development trend.The research on its anti-inflammatory,anti-tumor,alleviating oxidative stress,regulating endoplasmic reticulum stress and other mechanisms as well as the research and development of new drugs for ginsenosides have become the research hotspots in this field.

ginsenosideVOSviewerCiteSpaceresearch hotspotknowledge map

徐梦娇、晏军

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中国中医科学院望京医院,北京 100102

北京中医药大学东直门医院,北京 100700

人参皂苷 VOSviewer CiteSpace 研究热点 知识图谱

国家自然科学基金北京中医药大学东直门医院科技创新专项

81373589DZMKJCX-2020-027

2024

中国中医药图书情报杂志
中国中医科学院中医药信息研究所

中国中医药图书情报杂志

影响因子:0.556
ISSN:2095-5707
年,卷(期):2024.48(1)
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