首页|艾灸治疗腹泻型肠易激综合征研究进展

艾灸治疗腹泻型肠易激综合征研究进展

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  • 国家科技期刊平台
  • NETL
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肠易激综合征(IBS)在各年龄段均有发作,且以腹泻型肠易激综合征(IBS-D)最为多见.目前对IBS-D的具体发病机制尚未阐明,主要将其归因于神经-内分泌-免疫功能紊乱、内脏超敏反应、胃肠动力异常及精神心理因素等.中医学将IBS-D归属"泄泻""大肠泄"范畴,其病程较长,证型复杂多变,治疗难度大.本文对艾灸治疗IBS-D的研究进行综述,发现艾灸可通过刺激相应腧穴以调节核因子-κB信号通路、影响5-羟色胺受体、调节血管活性肠肽和P物质等神经递质、调控c-Kit/SCF信号轴及调整肠道菌群来缓解IBS-D的症状.
Research Progress in Moxibustion Treatment for Diarrhea-predominant Irritable Bowel Syndrome
Irritable bowel syndrome(IBS)is a common functional gastrointestinal disorder that can occur in all age groups,with diarrhea-predominant IBS(IBS-D)being the most common type.Currently,the specific pathogenesis of IBS-D has not been determined,and it is mainly attributed to neuroendocrine-immune dysfunction,visceral hyperalgesia,abnormal gastrointestinal motility,intestinal microbiota imbalance,abnormal bile acid absorption,and psychological factors.TCM categorizes IBS-D into the categories of"diarrhea"and"large intestine diarrhea",with a long course,complex and variable syndrome types,and high difficulty in treatment.This article reviewed the research on moxibustion treatment of IBS-D and found that moxibustion could regulate NF-κB signaling pathway by stimulating corresponding acupoints,affecting 5-HT receptors,regulating neurotransmitters,such as VIP and SP,regulating c-Kit/SCF signaling axis and gut microbiota to alleviate symptoms of IBS-D.

irritable bowel syndromemoxibustionmeridian acupointsinflammatory factorsintestinal florareview

杨灿灿、孙建华

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南京中医药大学附属医院,江苏 南京 210004

腹泻型肠易激综合征 艾灸 经络腧穴 炎症因子 肠道菌群 综述

国家自然科学基金面上项目国家自然科学基金面上项目国家中医药管理局中医药古籍文献和特色技术传承项目江苏省中医药管理局重点项目

8227463082174489GZY-KJS-2020-077ZD202224

2024

10.3969/j.issn.2095-5707.202309023

中国中医药图书情报杂志
中国中医科学院中医药信息研究所

中国中医药图书情报杂志

影响因子：0.556
ISSN：2095-5707
年,卷(期)：2024.48(2)
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