Exploration on the Treatment Law of Swollen-Head Epidemic in TCM Classics of Warm Pathogen Disease Based on Data Mining
Objective To analyze the syndrome differentiation and treatment principles of swollen-head epidemic in TCM classics of warm pathogen disease based on data mining methods.Methods The knowledge base of TCM classics of warm pathogen disease was retrieved.Ancient literature on warm pathogen disease was set as the data source,and data mining methods such as mathematical statistics,factor analysis,clustering analysis,and association rules were used to analyze the etiology,location,symptoms,treatment methods,and prescriptions of swollen-head epidemic.Results A total of 191 entries of literature on the swollen-head epidemic of warm pathogen disease were included,involving 31 ancient books,including Wen Du Bing Lun and Zhi Yi Quan Shu;the causes of swollen-head epidemic were mainly heat,poison,wind,warmth and seasonal qi,and most of the disease sites were found in the Yangming,Shaoyang,Taiyang,the interior,the heart,the lung,and the meridians;according to the symptoms,it could be classified into the six types of symptoms,namely,qi and blood burnt out syndrome,pathogens retained in the qi,pathogens and heat obstructed in the meridians,Shaoyang meridian syndrome,Yangming meridian syndrome,Wei meridian syndrome;and the treatment method was mainly based on heat-clearing,clearing and resolving,external application,and acupuncture;a total of 38 prescriptions and 118 kinds of Chinese materia medica were included,with heat-clearing,surface-relieving,orifice-opening,and external-application agents as the main ones,and Glycyrrhizae Radix et Rhizoma,Scutellariae Radix,Forsythiae Fructus,Platycodonis Radix,Scrophulariae Radix,and Coptidis Rhizoma occurring with high frequency.The results of association rules showed that the most supported pair was Scrophulariae Radix-Forsythiae Fructus.Bombyx Batryticatus,Isatidis Radix,Platycodonis Radix,Arctii Fructus,Scrophulariae Radix,Forsythiae Fructus appeared at the same time with high frequency,which was more consistent with the composition of Puji Xiaodu Decoction.Conclusion Swollen-head epidemic is primarily attributed to pathogenic wind and heat toxins.The significance of"Li Qi"(epidemic pathogen)should be emphasized.The disease primarily affects the head,and the pathogenic factors tend to linger in the lung and stomach.The clinical manifestations are closely related to the affected area of the head,often accompanied by other systemic symptoms around the body.The treatment approach commonly involves combining internal and external therapies.Compatibility of herbs are notable for their abilities to clear heat,detoxify,disperse wind,and eliminate pathogenic factors.Additionally,Puji Xiaodu Decoction and its modifications are commonly used in the treatment of swollen-head epidemic.
swollen-head epidemicknowledge base of TCM classics of warm pathogen diseasesyndrome differentiation and treatmentTCM classicsdata mining
国家科技期刊平台
NSTL
万方数据
