中药复方调控肠道菌群治疗脾肾虚损型骨质疏松症研究进展
Research Progress in the Treatment of Osteoporosis with Spleen-kidney Deficiency Type by Regulating Intestinal Flora with TCM Compounds
张亚衡 1周明旺 2王晓萍2
作者信息
- 1. 甘肃中医药大学,甘肃 兰州 730000
- 2. 甘肃省中医院,甘肃 兰州 730050
- 折叠
摘要
骨质疏松症属中医学"骨痿""骨枯"范畴,脾肾虚损可导致骨质疏松症发生,临床多见脾肾虚损型骨质疏松症.肠道菌群与骨质疏松症发生关系密切,本文从中医对骨质疏松症的认识、骨质疏松症与肠道菌群、脾肾虚损证与肠道菌群及中药复方调节肠道菌群治疗脾肾虚损型骨质疏松症进行综述,梳理中药复方对肠道菌群的调节作用及基于菌群介导的抗骨质疏松作用,为从微生物角度研究中药治疗骨质疏松症作用机制提供依据,为临床治疗提供研究思路.
Abstract
Osteoporosis belongs to the category of"bone impotence"and"bone withering"in TCM.Spleen-kidney deficiency can lead to the occurrence of osteoporosis,and osteoporosis with spleen-kidney deficiency type is mostly seen in clinical practice.The relationship between intestinal flora and osteoporosis is close.This article reviewed the understanding of osteoporosis in TCM,the relationship between osteoporosis and intestinal flora,the relationship between spleen-kidney deficiency and intestinal flora,as well as the Chinese herbal compound to regulate intestinal flora for the treatment of spleen-kidney deficiency osteoporosis,to rationalize the regulating effect of TCM prescriptions on the intestinal flora and the anti-osteoporosis effect based on the flora,and provide a basis for the study of the mechanism of TCM in the treatment of osteoporosis from the perspective of microorganism,and provide research ideas for the clinical treatment of osteoporosis.
关键词
肠道菌群/骨质疏松症/中药复方/脾肾虚损型/综述Key words
intestinal flora/osteoporosis/TCM compounds/spleen-kidney deficiency/review引用本文复制引用
基金项目
骨关节退行性疾病临床医学研究中心项目(18JR2FA009)
骨关节退行性疾病临床医学研究中心项目(2020-0411-SFC-0002)
全国老中医药专家学术经验继承工作项目(第七批)(2022)()
出版年
2024
国家科技期刊平台
NSTL
万方数据