首页|基于内质网应激探讨慢性冠脉综合征从脾治心内涵

基于内质网应激探讨慢性冠脉综合征从脾治心内涵

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中医学认为,心脾在生理、病理上紧密联系,脾病可致心病,心病可从脾治.内质网稳态和应激状态与中医脾的生理、病理相似,可能是中医脾功能在亚细胞层面的体现.内质网应激是慢性冠脉综合征的致病因素,通过参与动脉粥样硬化形成与血管内皮功能障碍促进慢性冠脉综合征进展,这与中医脾参与痰瘀形成,导致胸痹的过程相似.内质网应激与慢性冠脉综合征的联系为中医从脾治心、心脾同治提供参考,为中医药防治慢性冠脉综合征提供思路.
Discussion on the Connotation of Treating the Heart from the Spleen in Chronic Coronary Syndrome Based on Endoplasmic Reticulum Stress
According to TCM,the heart and spleen are closely linked in physiology and pathology;spleen diseases can lead to heart diseases,and heart diseases can be cured from the spleen.Endoplasmic reticulum homeostasis and stress are similar to the physiology and pathology of the spleen,and may be a reflection of spleen function at the subcellular level.Endoplasmic reticulum stress is a pathogenic factor in chronic coronary syndromes,and promotes the progression of chronic coronary syndromes by participating in the formation of atherosclerosis and vascular endothelial dysfunction,which is similar to the process of spleen involvement in the formation of phlegm and blood stasis leading to chest obstruction.The connection between ERS and chronic coronary syndromes provides a reference for the treatment of the heart from the spleen and treating the heart and spleen together in TCM,and provides ideas for the prevention and treatment of chronic coronary syndromes in TCM.

endoplasmic reticulum stresschronic coronary syndrometreating the heart from the spleen

徐镕锌、王晗

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南京中医药大学附属医院,江苏 南京 210029

内质网应激 慢性冠脉综合征 从脾治心

江苏省卫生健康委科研项目江苏省老年健康科研项目

BJ20021LKZ2023002

2024

中国中医药图书情报杂志
中国中医科学院中医药信息研究所

中国中医药图书情报杂志

影响因子:0.556
ISSN:2095-5707
年,卷(期):2024.48(4)
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