首页|基于数据挖掘分析中药热敷法治疗膝骨关节炎用药规律

基于数据挖掘分析中药热敷法治疗膝骨关节炎用药规律

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目的 利用数据挖掘分析中药热敷法治疗膝骨关节炎(KOA)用药规律,为临床提供参考.方法 检索中国知识资源总库(CNKI)、中文科技期刊数据库(VIP)、中国学术期刊数据库(万方数据)、中国生物医学文献数据库(CBM)建库至2022年3月20日收录的相关期刊文献,运用Excel2019软件对中药频次、性味归经、功效进行统计分析,运用SPSS Modeler 18.0软件Apriori算法对高频药物进行关联规则分析,利用SPSS Statistics 22.0软件进行聚类分析.结果 共纳入164首方剂,涉及175味中药,其中高频药物以红花、伸筋草、透骨草、川乌、草乌等祛风湿药为主;高频药物药性以温为多,药味以辛、苦为主,归经以肝经为主,功效以祛风湿为主,其次为发散风寒、活血调经.结论 中药热敷治疗KOA多从肝论之,兼顾脾肾,以祛风除湿、活血化瘀、通络祛痛为主要治法.
Analysis on the Medication Law of TCM Hot Compress for the Treatment of Knee Osteoarthritis Based on Data Mining
Objective To analyze the medication law of TCM hot compress in the treatment of knee osteoarthritis(KOA)using data mining;To provide reference for clinical practice.Methods Relevant journal literature was retrieved from CNKI,VIP,Wanfang Data and CBM from the establishment of the databases to 20th,March 2022.Excel 2019 software was used to statistically analyze the frequency,property and taste,meridian,and efficacy of Chinese materia medica.SPSS Modeler 18.0 software Apriori algorithm was used to perform association rule analysis on high-frequency drugs,and clustering analysis was performed using SPSS Statistics 22.0 software.Results A total of 164 prescriptions were included,involving 175 kinds of Chinese materia medica.Among them,high-frequency drugs mainly included anti rheumatic drugs such as Carthami Flos,Herba Lycopodii,Speranskia tuberculata(Bunge)Baill.,Aconiti Radix,Aconiti Kusnezoffii Radix;the medicinal property of high-frequency drugs was mainly warm,with pungent and bitterness as the main tastes.The meridian was mainly focused on the liver meridian,and the efficacy was mainly to dispel rheumatism.The second was to disperse wind and cold,promote blood circulation and regulate menstruation.Conclusion TCM hot compress for the treatment of KOA is mainly discussed from the liver,taking into account the spleen and kidney,with the main treatment methods of dispelling wind and dampness,promoting blood circulation and removing stasis,and unblocking collaterals and relieving pain.

knee osteoarthritisTCM hot compressdata miningmedication law

李丹阳、杜欣颖、黄壮

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北京大学第三医院北方院区,北京 100089

膝骨关节炎 中药热敷 数据挖掘 用药规律

2024

中国中医药图书情报杂志
中国中医科学院中医药信息研究所

中国中医药图书情报杂志

影响因子:0.556
ISSN:2095-5707
年,卷(期):2024.48(4)
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