基于"肝-肠"轴探讨痛泻要方治疗腹泻型肠易激综合征研究进展
Discussion on the Research Progress in the Treatment of Diarrheal Irritable Bowel Syndrome Based on"Liver-intestinal"Axis
毛国章 1卓立甬 2曹莞婷 1范一宏3
作者信息
- 1. 宁波市北仑区中医院,浙江 宁波 315800
- 2. 宁波市中医院,浙江 宁波 315012
- 3. 浙江省中医院,浙江 杭州 310006
- 折叠
摘要
运用中西医理论基于"肝-肠"轴探讨腹泻型肠易激综合征(IBS-D)发病机制,认为"肝-肠"轴失衡可能是IBS-D发病潜在机制.中医认为,肝与肠的联系主要依赖于脾,肝脾关系主要包括调节气机、统摄血液、调节情志等方面,"肝-肠"轴紊乱的核心在于肝脾不和,临床可应用痛泻要方治疗IBS-D,通过调节脑肠轴紊乱、肠黏膜稳态及肠道微生态发挥治疗作用.
Abstract
This article discussed the pathogenesis of diarrhea-predominant irritable bowel syndrome(IBS-D)using the theory of traditional Chinese and Western medicine.It was considered that the imbalance of"liver-intestinal"axis may be the potential mechanism of IBS-D.TCM believes that the relationship between liver and intestine mainly depends on the spleen.The relationship between liver and spleen mainly includes regulating qi movement,controlling blood,regulating emotions,etc.The core of"liver-intestinal"axis disorder lies in the disharmony between liver and spleen.Tongxie Yao Prescription can be used clinically to play a therapeutic role by regulating the disorder of brain-gut axis,intestinal mucosal homeostasis and intestinal microecology.
关键词
腹泻型肠易激综合征/"肝-肠"轴/痛泻要方/综述Key words
diarrhea-predominant irritable bowel syndrome/liver-intestinal axis/Tongxie Yao Prescription/review引用本文复制引用
出版年
2024