Analysis on the Medication Law of Ancient Prescriptions in Treating Lymphoma
Objective To analyze the medication law of ancient prescriptions in the treatment of lymphoma using data mining;To explore the changes of ancient and modern medication and the enlightenment to modern clinic by combining modern relevant literature.Methods Ancient prescriptions with names or indications containing"scrofula"and"phlegm kernel"were collected and organized.Excel 2019 was used to build a database.SPSS Statistics 25.0 was used to analyze the application frequency,and clustering analysis and complex network analysis were carried out.Python 3.10 was used for association rule analysis and Gephi0.9.2 was used for complex network analysis.Results A total of 259 ancient prescriptions were included,including 483 kinds of Chinese materia medica,with a total frequency of 2 256 times,among which 12 kinds of Chinese materia medica were used more than 30 times.The core medicines included Glycyrrhizae Radix et Rhizoma,Angelicae Sinensis Radix,Olibanum,Myrrha,Forsythiae Fructus,etc.Association rule analysis showed that the top four drug combinations with confidence were Olibanum-Myrrha,Olibanum-Angelicae Sinensis Radix,Myrrha-Angelicae Sinensis Radix,Angelicae Sinensis Radix-Glycyrrhizae Radix et Rhizoma.Five different functional drug combinations were obtained by clustering analysis,suggesting that the ancient prescriptions used in the treatment of lymphoma through the whole process of tonifying and invigorating healthy qi,with warming and dredging collaterals,clearing heat and reducing phlegm,reconcile nutritive level and nourishing blood,dispelling wind and clear Xuanfu,soothing liver and strengthening spleen and other treatment methods.Conclusion The ancient and modern drugs used in lymphoma are basically consistent.The ancient prescriptions attached great importance to the application of antisuperficial drugs.The proportion of phlegm reducing drugs in modern clinical application increases,and high frequency drugs such as Angelicae Sinensis Radix have special significance in the treatment of lymphoma.
万方数据
维普
