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基于数据挖掘分析中医药治疗上气道咳嗽综合征用药规律

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目的 利用数据挖掘方法研究中医药治疗上气道咳嗽综合征(UACS)的用药规律,以指导临床遣方用药。方法 检索中国知识资源总库(CNKI)、中国学术期刊数据库(万方数据)、中文科技期刊数据库(VIP)建库至2023年10月9日收录的中医药治疗UACS文献,将筛选后的处方建立数据库,运用Excel2019对药物进行频次、功效及性味归经分析,分别运用SPSS Modeler 18。0及SPSS Statistics 26。0进行关联规则分析和系统聚类分析。结果 纳入有效处方186首,涉及中药209味,高频药物为甘草、辛夷、桔梗、苍耳子、苦杏仁等;药物类型以解表药、化痰平喘止咳药、清热药、补益药为主;药性以温、寒、平为主;药味以辛、苦、甘为主;归经以肺经、胃经、脾经为主。关联规则得出11组核心药对,聚类分析将高频药物分为8类。结论 中医药治疗UACS多从风痰论治,采用祛风解表、化痰通窍、止咳平喘、燥湿理气等治法,常用苍耳子散、止嗽散、小青龙汤、玉屏风散、二陈汤。
Analysis on the Medication Law in the Treatment of Upper Airway Cough Syndrome Based on Data Mining
Objective To discuss the medication law in TCM treatment of upper airway cough syndrome(UACS)based on data mining methods;To guide clinical medication.Methods The clinical research literature on TCM treatment of UACS was retrieved from CNKI,VIP and Wangfang from the establishment of the databases to October 9,2023.A database of screened prescriptions was established.Analysis on frequency,efficacy,property and taste,and meridian was performed by Excel 2019.Association rule analysis and systematic clustering analysis of drugs were performed by SPSS Modeler 18.0 and SPSS Statistics 26.0,respectively.Results Totally 186 effective prescriptions were included,involving 209 kinds of Chinese materia medica.The drugs with high frequency of use were Glycyrrhizae Radix et Rhizoma,Magnoliae Flos,Platycodonis Radix,Xanthii Fructus,Armeniacae Semen Amarum;the main types of drugs were antipyretic drugs,antiasthmatic drugs,heat-clearing drugs and tonifying drugs;the drug properties were mainly warm,cold and neutral;the tastes were mainly pungent,bitter and sweet;the meridians were mainly the lung,stomach and spleen meridians.11 core medicinal pairs were obtained by association rules,and high frequency drugs were divided into 8 categories by clustering analysis.Conclusion The TCM treatment of UACS is mainly based on wind and phlegm,mainly to dispel wind and exterior,dissipate phlegm and open the orifices,relieve cough and asthma,dry dampness and regulate qi.Commonly used prescriptions are Cang'erzi Powder,Zhisou Powder,Xiaoqinglong Decoction,Yupingfeng Powder,and Erchen Decoction.

upper airway cough syndromeTCM treatmentdata miningmedication law

叶新萌、彭波、叶静、毛景泽

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成都中医药大学临床医学院,四川 成都 610075

成都中医药大学附属医院,四川 成都 610075

成都中医药大学基础医学院,四川 成都 611137

上气道咳嗽综合征 中医药治疗 数据挖掘 用药规律

2024

中国中医药图书情报杂志
中国中医科学院中医药信息研究所

中国中医药图书情报杂志

影响因子:0.556
ISSN:2095-5707
年,卷(期):2024.48(6)