首页|中医药治疗功能性消化不良肝郁脾虚证临床疗效及作用机制研究进展

中医药治疗功能性消化不良肝郁脾虚证临床疗效及作用机制研究进展

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功能性消化不良为临床常见功能性胃肠疾病,具有发病率高、不易治愈、病情反复等特点。功能性消化不良属中医学"痞满""胃脘痛"等范畴,病位在胃,与肝、脾密切相关,常见肝郁脾虚证。本文归纳中医药治疗功能性消化不良肝郁脾虚证相关文献,针对临床应用、疗效特点、作用机制等进行总结,为临床治疗及基础研究提供参考。分析发现,中医药治疗功能性消化不良临床疗效显著,在改善患者消化症状同时,还可改善其焦虑抑郁状态及日常生活质量,具有整体调节、辨证施治、改善体质的特点,其作用机制可能涉及胃动力异常、脑肠互动异常及免疫炎症反应等多途径、多层次。
Research Progress in the Clinical Efficacy and Mechanism of TCM for the Treatment of Functional Dyspepsia with Liver Depression and Spleen Deficiency Syndrome
Functional dyspepsia(FD)is a common functional gastrointestinal disease in clinical practice,which has the characteristics of high incidence,difficult to cure,and recurrence.FD belongs to the categories of"ruffian"and"stomach pain"in TCM,and the disease is located in the stomach,which is closely related to the liver and spleen,and the syndrome of liver depression and spleen deficiency is the most common.This article summarized the literature related to the TCM treatment for FD with liver depression and spleen deficiency syndrome,and concluded the clinical application,efficacy characteristics and mechanism,so as to provide reference for clinical treatment and basic research.The analysis found that the clinical efficacy of TCM in the treatment of FD is significant,which can not only improve the digestive symptoms of patients,but also improve their anxiety and depression state and daily life quality,and has the characteristics of overall regulation,syndrome differentiation and treatment,and improvement of physical fitness.Its mechanism may involve multiple pathways and levels such as abnormal gastric motility,abnormal brain-intestinal interaction and immune inflammatory response.

functional dyspepsialiver depression and spleen deficiency syndromeefficacymechanismreview

安成飞、陈英英、宁静、李华南、张玮、包安、刘书芹、谭涛

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天津中医药大学第一附属医院,国家中医针灸临床医学研究中心,国家中医药管理局推拿手法生物效应三级实验室,天津 300193

功能性消化不良 肝郁脾虚 疗效 机制 综述

2025

中国中医药信息杂志
中国中医科学院中医药信息研究所

中国中医药信息杂志

影响因子:0.889
ISSN:1005-5304
年,卷(期):2025.32(1)