State Key Laboratory of Targeting Oncology,National Center for International Research of Bio-targeting Theranostics,Guangxi Key Laboratory of Bio-targeting Theranostics,Collaborative Innovation Center for Targeting Tumor Diagnosis and Therapy,Guangxi Talent Highland of Bio-targeting Theranostics,Guangxi Medical University,Nanning,Guangxi 530021,China

State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers and National Clinical Research Center for Digestive Diseases,Xijing Hospita

Key Laboratory of Resource Biology and Biotechnology in Western China,Ministry of Education,School of Medicine,Northwest University,Xi'an,Shaanxi 710000,China

Key Laboratory of Dairy Biotechnology and Engineering,Ministry of Education,Key Laboratory of Dairy Products Processing,Ministry of Agriculture and Rural Affairs,Inner Mongolia Key Laboratory of Dairy Biotechnology and Engineering,Inner Mongolia Agricultural University,Hohhot,Inner Mongolia 010018,China

State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers and National Clinical Research Center for Digestive Diseases,Xijing Hospital of Digestive Diseases,Fourth Military Medical University,Xi'an,Shaanxi 710032,China