首页|Gallbladder polypoid lesions:Current practices and future prospects

Gallbladder polypoid lesions:Current practices and future prospects

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Gallbladder polypoid lesions(GPLs)refer to any elevated lesion of the mucosal surface of the gallbladder wall,and the prevalence is estimated to be between 0.9%and 12.1%.GPLs include benign polyps and malignant polyps.Benign polyps are further classified as non-neoplastic polyps and neoplastic polyps.Cholesterol polyps are the most common benign polyps and adenocarcinoma is the main type of malignant polyp.Hepatitis B virus infection,liver function abnormalities,dyslipidemia,and obesity are the main risk factors for GPLs.Studies of biological mechanisms have focused on malignant gallbladder polyps,the development of which is regulated by hormone levels in vivo,gut microbiota,inflammation,oxidative stress,Salmonella typhimurium,and related molecules.Diagnostic modalities include chemical examination and imaging examination,with imaging examination currently being the mainstay.Treatment of patients with GPLs is based on the presence or absence of symptoms,age,size of the polyps,tendency of the polyp to increase,and risk factors for symptomatic malignancy to determine whether surgery should be performed.

Gallbladder neoplasmsBenign polypsMalignant polypsRisk factorsBiological mechanismDiagnosisTreatment

Kun Wang、Qingpeng Xu、Lu Xia、Jianing Sun、Kanger Shen、Haoran Liu、Linning Xu、Rui Li

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Department of Gastroenterology,The First Affiliated Hospital of Soochow University,Suzhou,Jiangsu 215026,China.

Jiangsu Province-Establishment of an endoscopic diagnosis and treatment system for submucosal tumors of the digestive tract and

BE2019667

2024

中华医学杂志(英文版)
中华医学会

中华医学杂志(英文版)

CSTPCD
影响因子:0.838
ISSN:0366-6999
年,卷(期):2024.137(14)
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