首页|Regulation of fatty acid synthase on tumor and progress in the development of related therapies

Regulation of fatty acid synthase on tumor and progress in the development of related therapies

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Fatty acid synthase(FASN)is an essential molecule in lipid metabolic pathways,which are crucial for cancer-related studies.Recent studies have focused on a comprehensive understanding of the novel and important regulatory effects of FASN on malignant biological behavior and immune-cell infiltration,which are closely related to tumor occurrence and development,immune escape,and immune response.FASN-targeting antitumor treatment strategies are being developed.Therefore,in this review,we focused on the effects of FASN on tumor and immune-cell infiltration and reviewed the progress of related anti-tumor therapy development.

NeoplasmFatty acid synthaseFatty acid synthase inhibitorImmune regulation

Rilan Bai、Jiuwei Cui

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Cancer Center,the First Hospital of Jilin University,Changchun,Jilin 130021,China

吉林省科技厅项目Jilin Provincial Department of Finance Project

20190303146SFJLSWSRCZX2020-0023

2024

中华医学杂志(英文版)
中华医学会

中华医学杂志(英文版)

CSTPCD
影响因子:0.838
ISSN:0366-6999
年,卷(期):2024.137(16)