首页|Chinese national clinical practice guidelines on prevention,diagnosis and treatment of early colorectal cancer

Chinese national clinical practice guidelines on prevention,diagnosis and treatment of early colorectal cancer

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Background:The incidence and mortality of colorectal cancer(CRC)in China are increasing in recent years.The clarified patho-genesis and detectable precancerous lesions of CRC make it possible to prevent,screen,and diagnose CRC at an early stage.With the development of endoscopic and surgical techniques,the choice of treatment for early CRC is also worth further discussion,and accordingly,a standard follow-up program after treatment needs to be established.Methods:This clinical practice guideline(CPG)was developed following the recommended process of the World Health Organi-zation,adopting Grading of Recommendations Assessment,Development and Evaluation(GRADE)in assessing evidence quality,and using the Evidence to Decision framework to formulate clinical recommendations,thereby minimizing bias and increasing transparency of the CPG development process.We used the Reporting Items for practice Guidelines in HealThcare(RIGHT)statement and Appraisal of Guidelines for Research and Evaluation Ⅱ(AGREE Ⅱ)as reporting and conduct guides to ensure the guideline's completeness and transparency.Results:This CPG comprises 46 recommendations concerning prevention,screening,diagnosis,treatment,and surveillance of CRC.In these recommendations,we have indicated protective and risk factors for CRC and made recommendations for che-moprevention.We proposed a suitable screening program for CRC based on the Chinese context.We also provided normative statements for the diagnosis,treatment,and surveillance of CRC based on existing clinical evidence and guidelines.Conclusions:The 46 recommendations in this CPG are formed with consideration for stakeholders'values and preferences,feasibility,and acceptability.Recommendations are generalizable to resource-limited settings with similar CRC epidemiology pattern as China.

Colorectal cancerEarly detection of cancerPreventionScreeningDiagnosisTreatmentFollow-upGuideline

Jingnan Li、Hongwei Yao、Yun Lu、Shutian Zhang、Zhongtao Zhang、Society of Digestive Endoscopy of the Chinese Medical Association、Colorectal Surgery Group of the Chinese Medical Association、Chinese Association of Gastroenterologist & Hepatol-ogist、National Clinical Research Center for Digestive Diseases、Chinese Medical Journal Clinical Practie Guideline Collaborative

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Department of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100730, China

Department of General Surgery,Beijing Friendship Hospital,Capital Medical University,National Clinical Research Center for Digestive Diseases,Beijing 100050,China

Department of General Surgery,The Affiliated Hospital of Qingdao University,Qingdao,Shandong 266555,China

Department of Gastroenterology,Beijing Friendship Hospital,Capital Medical University,National Clinical Research Center for Digestive Disease,Beijing 100050,China

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2024

中华医学杂志(英文版)
中华医学会

中华医学杂志(英文版)

CSTPCD
影响因子:0.838
ISSN:0366-6999
年,卷(期):2024.137(17)