首页|Impact of pancreatic and biliary stent on post-endoscopic papillectomy complications:A single-center retrospective study
Impact of pancreatic and biliary stent on post-endoscopic papillectomy complications:A single-center retrospective study
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国家科技期刊平台
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NSTL
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Background:Endoscopic papillectomy(EP)is recommended as the first-line therapy for ampullary tumors,despite a relatively high incidence of complications.Pancreatic and/or biliary stents are placed at the endoscopist's discretion to prevent post-EP complications.The present study aimed to evaluate the efficacy of different stents.Methods:A total of 117 patients who underwent EP and met the criteria between June 2006 and October 2022 were enrolled in the study.These patients were divided into a pancreatic stent group(PS group,n=47),a biliary stent group(BS group,n=38),and a two-stent group(PBS[PS and BS]group,n=32).Relevant clinical data were collected and compared among the three groups.Multivariate logistic analyses were performed to explore risk factors for post-EP complications.Results:The incidence of all complications was 37.6%(44/117).Pancreatitis and hemorrhage were the two most common complications with incidence rates of 14.5%(17/117)and 17.9%(21/117).The incidence rates of post-EP pancreatitis were 10.6%(5/47),23.7%(9/38),and 9.4%(3/32)in the PS group,BS group,and PBS group,respectively,with no significant differences.There were also no significant differences in other complications among the three groups.Age(odds ratio[OR]:0.95;95%confidence interval[CI]:0.91-0.99;P=0.022)was independently associated with post-EP pancreatitis while tumor size(OR:1.66;95%CI:1.06-2.60;P=0.028)was independently associated with post-EP hemorrhage.Conclusions:While pancreatic stenting is the first choice to prevent post-EP pancreatitis,biliary stenting could also be considered as a substitute for patients with difficulties in pancreatic cannulation.Two-stent(biliary and pancreatic stent)placement is unnecessary unless it is required due to other concerns.