首页|Tuberculosis in infertility and in vitro fertilization-embryo transfer

Tuberculosis in infertility and in vitro fertilization-embryo transfer

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Tuberculosis(TB)is a prominent infectious disease globally that imposes a substantial health burden.Genital TB(GTB),an extrapul-monary manifestation,leads to complications such as tubal adhesions,blockage,and diminished ovarian function,culminating in infertility,and is recognized as a prevalent cause of infertility in nations with high-burden TB.In regions with low TB rates,infertility and active TB during pregnancy have been reported to be most common among female immigrants from countries with high-burden TB.In the context of TB,pregnant women often exhibit exacerbated symptoms after in vitro fertilization-embryo transfer(IVF-ET),heightening the risk of dissemination.Miliary pulmonary TB and tuberculous meningitis pose a serious threat to maternal and fetal health.This article integrates recent epidemiological data and clinical research findings,delineating the impact of TB on infertility and assisted reproduction and particularly focusing on the diagnosis and treatment of GTB,underscored by the imperative of TB screening before IVF-ET.Our objective is to increase awareness among respiratory and reproductive health professionals,promoting multidisciplinary management to enhance clinical vigilance.This approach seeks to provide patients with judicious reproductive plans and scientifically rigorous pregnancy management,thereby mitigating adverse pregnancy outcomes related to TB activity.

InfertilityGenital tuberculosisPregnancyIn vitro fertilization-embryo transferTuberculosis screeningFertilization in vitro

Xiaoyan Gai、Hongbin Chi、Rong Li、Yongchang Sun

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Department of Respiratory and Critical Care Medicine,Peking University Third Hospital,Research Center for Chronic Airway Diseases,Peking University Health Science Center,Beijing 100191,China

Center for Reproductive Medicine,Department of Obstetrics and Gynecology,Peking University Third Hospital,National Clinical Research Center for Obstetrics and Gynecology,Beijing 100191,China

Capital's Funds for Health Improvement and ResearchCohort Projects of Peking University Third HospitalKey Clinical Projects of Peking University Third Hospital

2022-2G-40910BYSYDL2019005BYSYZD2022014

2024

中华医学杂志(英文版)
中华医学会

中华医学杂志(英文版)

CSTPCD
影响因子:0.838
ISSN:0366-6999
年,卷(期):2024.137(20)
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