首页|Growing burden of inflammatory bowel disease in China:Findings from the Global Burden of Disease Study 2021 and predictions to 2035

Growing burden of inflammatory bowel disease in China:Findings from the Global Burden of Disease Study 2021 and predictions to 2035

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Background:Inflammatory bowel disease(IBD)imposes a significant economic and social burden in China.We aim to assess the epidemiological trends of IBD in China,and to predict the burden in the near future.Methods:The incidence,mortality,prevalence,and disability-adjusted life year(DALYs)of IBD from 1990 to 2021 were obtained from Global Burden of Disease Study 2021.Estimated annual percentage change(EAPC),average annual percent change,total percent change,and age-period-cohort model were used to access trends.Bayesian age-period-cohort model was utilized to predict the risk of incidence and mortality.Results:In 2021,IBD affected 168,077 people in China,with 24,941 new cases and 5640 deaths.The age-standardized rate(ASR)of incidence and death was 1.4 and 0.3,respectively.The incidence and prevalence in China were lower than the global and high socio-demographic index(SDI)regions,but the ASR of incidence and prevalence(EAPC:2.93 and 2.54,respectively)had rapidly increased from 1990 to 2021.The ASR of death and DALYs had significantly decreased(EAPC:-3.05 and-2.93,respectively).Middle-aged and elderly populations faced a severe burden of incidence and prevalence,while the elderly population faced a severe mortality burden.It is projected that by 2035,the ASR of incidence will continue to rise,whereas the death rate will continue to decline.Conclusions:The burden of IBD in China is serious and increasingly severe.Establishing a comprehensive disease management system in China will help better control the medical burden of IBD.

Inflammatory bowel diseaseIncidencePrevalenceGlobal Burden of DiseaseDisease burdenChina

Ziqing Yu、Gechong Ruan、Xiaoyin Bai、Yinghao Sun、Hong Yang、Jiaming Qian

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Department of Gastroenterology,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences & Peking Union Medical College,Beijing 100730,China

2024

中华医学杂志(英文版)
中华医学会

中华医学杂志(英文版)

CSTPCD
影响因子:0.838
ISSN:0366-6999
年,卷(期):2024.137(23)