Expert consensus on the diagnosis and treatment of coagulation disorders in the acute phase of traumatic brain injury(version 2024)
The high incidence of coagulation disorders in the acute phase after traumatic brain injury significantly increases the risks of progressive intracranial hemorrhage and massive intraoperative bleeding,the difficulty of treatment and the mortality rate of the patients.The main pathological mechanism for coagulation disorders in the acute phase after traumatic brain injury is that a large number of tissue factors become exposed to result in an aberrant activation of coagulation,so it is a special type of trauma-induced coagulopathy.Coagulation disorder in the acute phase after traumatic brain injury has an insidious onset that is often not associated with massive bleeding,leading to non-standardized diagnosis and treatment.Currently,there is a lack of relevant consensus or guideline.For this purpose,Neurotrauma Committee of the National Trauma Center and Neurocritical Care Expert Committee of Branch of Neurological Surgeons of Chinese Medical Doctor Association have organized relevant domestic experts to jointly formulate Expert consensus on the diagnosis and treatment of coagulation disorders in the acute phase of traumatic brain injury(version 2024)with reference to the latest guidelines,consensuses,and clinical researches in relevant fields at home and abroad and expert advice collected through the modified Delphi method.Eighteen recommendations have been proposed for the diagnosis and treatment of coagulation disorders in the acute phase of traumatic brain injury,aiming to standardize its diagnosis and treatment in the clinical settings.
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