Abstract
Pericyte,a kind of pluripotent cell,may regulate the irrigation flow and permeability of microcirculation.Pericytes are similar to the smooth muscle cells,which express several kinds of contractile proteins and have contractility.The dysfunction of pericytes is related to many microvascular diseases,including hypoxia,hypertension,diabetic retinopathy,fibrosis,inflammation,Alzheimer's disease,multiple sclerosis,and tumor formation.For a long time,their existence and function have been neglected.The distribution,structure,biomarker,related signaling pathways as well as the roles of pericytes on vascular diseases will be introduced in this review.
基金项目
This study was supported by the Key Projects and innovation group of National Natural Science Foundation of China(81721001)
These funding agencies had no role in study design,collection/analyses of data,decision to publish,or manuscript prepar()
NETL
NSTL
维普
万方数据