New perspectives on traumatic bone infections

Ruo-Hui Tang ¹Jing Yang ²Jun Fei³

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作者信息

1. Health Team of 96824 Troops of the Chinese People's Liberation Army,Kunming,China
2. Emergency Department,Daping Hospital,Third Military Medical University,Chongqing,China
3. Emergency Department,Daping Hospital,Third Military Medical University,Chongqing,China;State Key Laboratory of Trauma,Burns and Combined Injury,Third Military Medical University,Chongqing,China
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Abstract

In this paper,we review the results of previous studies and summarize the effects of various factors on the regulation of bone metabolism in traumatic bone infections.Infection-related bone destruction in-corporates pathogens and iatrogenic factors in the process of bone resorption dominated by the skeletal and immune systems.The development of bone immunology has established a bridge of communication between the skeletal system and the immune system.Exploring the effects of pathogens,skeletal sys-tems,immune systems,and antibacterials on bone repair in infectious conditions can help improve the treatment of these diseases.

Key words

Bone infection/Bone destruction/Osteoclasts/Immunomodulation

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基金项目

study was supported by Medical Research Funding of PLA of China(AWS14C003)

Special Funds for Social Un-dertaking and Livelihood Security Projects of Chongqing(CSTC2016SHMSZX130068)

Youth Development Program of Medical Technology of PLA(16QNP103)

and Scientific and Medical Research Project of Chongqing(num-ber:2018ZDXM030)

出版年

2020

中华创伤杂志(英文版)

中华医学会

中华创伤杂志(英文版)

CSTPCDCSCD

影响因子：0.608

ISSN：1008-1275

参考文献量55

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