Abstract
Trauma-induced pulmonary thromboembolism is the second leading cause of death in severe trauma patients.Primary fibrinolytic hyperactivity combined with hemorrhage and consequential hypercoagu-lability in severe trauma patients create a huge challenge for clinicians.It is crucial to ensure a safe anticoagulant therapy for trauma patients,but a series of clinical issues need to be answered first,for example,what are the risk factors for traumatic venous thromboembolism?How to assess and deter-mine the status of coagulation dysfunction of patients?When is the optimal timing to initiate phar-macologic prophylaxis for venous thromboembolism?What types of prophylactic agents should be used?How to manage the anticoagulation-related hemorrhage and to determine the optimal timing of restarting chemoprophylaxis?The present review attempts to answer the above questions.
基金项目
Chaoyang District Bureau of Science and Technology and Information Technology(Bureau of Big Data).Contract no.CYSF 2049.The fund()
NETL
NSTL
万方数据