首页|Advances in mesenchymal stem cells therapy for tendinopathies

Advances in mesenchymal stem cells therapy for tendinopathies

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Tendinopathies are chronic diseases of an unknown etiology and associated with inflammation.Mesenchymal stem cells(MSCs)have emerged as a viable therapeutic option to combat the pathological progression of tendinopathies,not only because of their potential for multidirectional differentiation and self-renewal,but also their excellent immunomodulatory properties.The immunomodulatory effects of MSCs are increasingly being recognized as playing a crucial role in the treatment of tendinopathies,with MSCs being pivotal in regulating the inflammatory microenvironment by modulating the immune response,ultimately contributing to improved tissue repair.This review will discuss the current knowledge regarding the application of MSCs in tendinopathy treatments through the modulation of the immune response.

Mesenchymal stem cellsTendinopathyImmunomodulationTreatmentReview

Xu-Feng Mao、Xi-Qian Zhang、Zhe-Yu Yao、Hai-Jiao Mao

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Department of Orthopaedic Surgery,The First Affiliated Hospital of Ningbo University,Ningbo,315010,Zhejiang province,China

Medical Health Project of the Health Department of Zhejiang ProvinceNingbo Public Welfare Science and Technology ProjectNingbo Major Science and Technology ProjectZhejiang Provincial Natural Science Foundation of China

2021KY10452021S1042022Z133LBY23H180002

2024

10.1016/j.cjtee.2023.11.002

中华创伤杂志(英文版)
中华医学会

中华创伤杂志(英文版)

CSTPCD
影响因子：0.608
ISSN：1008-1275
年,卷(期)：2024.27(1)
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