Abstract
Tendinopathies are chronic diseases of an unknown etiology and associated with inflammation.Mesenchymal stem cells(MSCs)have emerged as a viable therapeutic option to combat the pathological progression of tendinopathies,not only because of their potential for multidirectional differentiation and self-renewal,but also their excellent immunomodulatory properties.The immunomodulatory effects of MSCs are increasingly being recognized as playing a crucial role in the treatment of tendinopathies,with MSCs being pivotal in regulating the inflammatory microenvironment by modulating the immune response,ultimately contributing to improved tissue repair.This review will discuss the current knowledge regarding the application of MSCs in tendinopathy treatments through the modulation of the immune response.
基金项目
Medical Health Project of the Health Department of Zhejiang Province(2021KY1045)
Ningbo Public Welfare Science and Technology Project(2021S104)
Ningbo Major Science and Technology Project(2022Z133)
Zhejiang Provincial Natural Science Foundation of China(LBY23H180002)
NETL
NSTL
万方数据