Abstract
Sepsis is a potentially fatal condition characterized by the failure of one or more organs due to a disordered host response to infection.The development of sepsis is closely linked to immune dysfunc-tion.As a result,immunotherapy has gained traction as a promising approach to sepsis treatment,as it holds the potential to reverse immunosuppression and restore immune balance,thereby improving the prognosis of septic patients.However,due to the highly heterogeneous nature of sepsis,it is crucial to carefully select the appropriate patient population for immunotherapy.This review summarizes the current and evolved treatments for sepsis-induced immunosuppression to enhance clinicians'under-standing and practical application of immunotherapy in the management of sepsis.
基金项目
国家自然科学基金(82302415)
国家自然科学基金(82272186)
国家自然科学基金(82002076)
广东省自然科学基金(2016A030313269)
Sun Yatsen University Clinical Research Program 5010(2019002)
Guangdong Clinical Research Center for Critical Care Medicine(2020B1111170005)
NETL
NSTL
万方数据