首页|Clinical practice of sepsis-induced immunosuppression:Current immunotherapy and future options

Clinical practice of sepsis-induced immunosuppression:Current immunotherapy and future options

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Sepsis is a potentially fatal condition characterized by the failure of one or more organs due to a disordered host response to infection.The development of sepsis is closely linked to immune dysfunc-tion.As a result,immunotherapy has gained traction as a promising approach to sepsis treatment,as it holds the potential to reverse immunosuppression and restore immune balance,thereby improving the prognosis of septic patients.However,due to the highly heterogeneous nature of sepsis,it is crucial to carefully select the appropriate patient population for immunotherapy.This review summarizes the current and evolved treatments for sepsis-induced immunosuppression to enhance clinicians'under-standing and practical application of immunotherapy in the management of sepsis.

SepsisSepsis-induced immunosuppressionImmunotherapyEnrichmentClassifier

Fei Pei、Bin Gu、Shu-Min Miao、Xiang-Dong Guan、Jian-Feng Wu

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Department of Critical Care Medicine,The First Affiliated Hospital,Sun Yat-sen University,Guangzhou,510080,China

Guangdong Clinical Research Center for Critical Care Medicine,Guangzhou,510080,China

国家自然科学基金国家自然科学基金国家自然科学基金广东省自然科学基金Sun Yatsen University Clinical Research Program 5010Guangdong Clinical Research Center for Critical Care Medicine

8230241582272186820020762016A03031326920190022020B1111170005

2024

10.1016/j.cjtee.2023.11.001

中华创伤杂志(英文版)
中华医学会

中华创伤杂志(英文版)

CSTPCD
影响因子：0.608
ISSN：1008-1275
年,卷(期)：2024.27(2)
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