中华耳鼻咽喉头颈外科杂志2024,Vol.59Issue(1) :12-20.DOI:10.3760/cma.j.cn115330-20230721-00012

内镜下颞下窝良性肿物手术切除的临床疗效和安全性分析

The efficacy and safety analysis of endoscopic resection for infratemporal fossa benign mass

黄振校 黄谦 崔顺九 马晶影 霍明瑞 阳铨杰 周兵
中华耳鼻咽喉头颈外科杂志2024,Vol.59Issue(1) :12-20.DOI:10.3760/cma.j.cn115330-20230721-00012

内镜下颞下窝良性肿物手术切除的临床疗效和安全性分析

The efficacy and safety analysis of endoscopic resection for infratemporal fossa benign mass

黄振校 1黄谦 1崔顺九 1马晶影 1霍明瑞 1阳铨杰 1周兵1
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作者信息

  • 1. 首都医科大学附属北京同仁医院耳鼻咽喉头颈外科,北京 100730
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摘要

目的 分析内镜下手术治疗颞下窝肿物的疗效和安全性.方法 本研究为回顾性病例系列研究,纳入于2008年4月至2021年12月在首都医科大学附属北京同仁医院鼻科接受内镜手术治疗的颞下窝肿物患者29例,其中男性10例,女性19例,年龄(46.5±13.7)岁.术前和术后分别行鼻窦CT、鼻咽或鼻窦增强MRI评估.主要结局测量指标为肿物全部切除率,以及手术相关并发症发生情况.结果 本研究29例颞下窝肿物包含神经鞘瘤22例、囊肿3例、神经纤维瘤2例、多形性腺瘤1例、基底细胞腺瘤1例.术前影像学检查提示肿物周围界限清晰,术后组织病理学检查均提示为良性病变.28例患者采用内镜经鼻人路,1例采用内镜经鼻入路联合内镜经口入路,肿物全部切除率为100%.平均随访时间38个月(7~168个月),未见肿物复发.结论 内镜经鼻人路可用于切除颞下窝良性肿物,疗效满意且安全性较高.

Abstract

Objective To investigate the efficacy and safety of endoscopic resection of infratemporal fossa mass and to determine the indications for surgery.Methods A retrospective case series study was conducted,including a total of 29 patients who underwent endoscopic surgery to treat infratemporal fossa mass in the Department of Rhinology of Beijing Tongren Hospital,Capital Medical University,from April 2008 to December 2021.Ten males and 19 females were included in the study,with age of(46.5±13.7)years.Pre-and post-operative sinus CT,sinus or nasopharyngeal enhanced MRI were evaluated,respectively.The main outcome measurements were the total resection of mass and the incidence of surgery-related complications.Results Among the 29 cases of infratemporal fossa mass,22 were schwannomas,3 were cysts,2 were neurofibromas,1 was pleomorphic adenoma and 1 was basal cell adenoma.Preoperative imaging showed well-defined lesion boundaries,and postoperative pathology confirmed the benign nature of all cases.The endoscopic transnasal approach was used in 28 patients,while the combination of the transnasal approach and the transoral approach was used in 1 patient.Complete tumor removal was achieved in all cases with a 100%resection rate.The average follow-up time was 38 months(7-168 months),and no tumor recurrence was observed.Conclusions The Endoscopic transnasal approach is a safe and effective surgical approach for the treatment of benign tumors or masses in the infratemporal fossa.

关键词

内镜手术/经鼻入路/颞下窝肿物/疗效/安全性

Key words

Endoscopic surgery/Transnasal approach/Infratemporal fossa mass/Efficacy/Safety

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基金项目

国家自然科学基金(81770977)

北京市科技委员会首都特色应用研究专项(Z181100001718103)

首都医科大学附属北京同仁医院重点医学专项基金资助课题(trdzyxzy201702)

Beijing Municipal Science & Technology Commission(Z18110000171803)

Clinical Medicine Development of Special Funding Support in Beijing Tongren Hospital,Capital Medical University(trzdyxy201702)

出版年

2024
中华耳鼻咽喉头颈外科杂志
中华医学会

中华耳鼻咽喉头颈外科杂志

CSTPCDCSCD北大核心
影响因子:1.727
ISSN:1673-0860
参考文献量16
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