中华耳科学杂志2023,Vol.21Issue(5) :696-700.DOI:10.3969/j.issn.1672-2922.2023.05.015

阿尔茨海默病与听功能障碍相关性研究进展

Research Progress on the Correlation between Alzheimer's Disease and Hearing Dysfunction

吴远程 谢道莉 王述立 郑体花 郑庆印 李博
中华耳科学杂志2023,Vol.21Issue(5) :696-700.DOI:10.3969/j.issn.1672-2922.2023.05.015

阿尔茨海默病与听功能障碍相关性研究进展

Research Progress on the Correlation between Alzheimer's Disease and Hearing Dysfunction

吴远程 1谢道莉 1王述立 1郑体花 1郑庆印 1李博1
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作者信息

  • 1. 滨州医学院特殊教育学院听力与言语康复研究院(烟台 264003)
  • 折叠

摘要

阿尔茨海默病(Alzheimer's disease,AD)是一种起病隐匿、进行性加重的神经退行性疾病,是导致痴呆最常见的病因.近年来研究发现AD常伴有听功能障碍,此外还有研究证实周围听功能障碍是AD的独立危险因素,因此AD与听功能障碍的相关性成为新的研究热点.本文将对AD与听功能障碍之间的联系及其机制、AD患者和动物模型的听功能障碍特征、听力干预对AD的影响做一综述,为AD的预防和临床诊治提供参考.

Abstract

Alzheimer's disease(AD)is a neurodegenerative disease with insidious onset and progressive aggrava-tion.It is the most common cause of dementia.In recent years,studies have found that AD is often accompanied by audi-tory dysfunction.In addition,some studies have confirmed that peripheral auditory dysfunction is an independent risk factor for AD.The correlation between AD and auditory dysfunction has become a new research focus.This article will review the relationship between AD and auditory dysfunction and its mechanism,the characteristics of auditory dysfunc-tion in AD patients and animal models,and the impact of hearing intervention on AD,so as to provide a basis for the pre-vention,clinical diagnosis and treatment of AD.

关键词

阿尔茨海默病/听功能障碍/认知功能障碍/痴呆

Key words

Alzheimer's disease/Hearing disorders/Cognitive disorders/Dementia

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基金项目

国家自然科学基金-面上项目()

国家自然科学基金-重点项目(82371137)

国家自然科学基金-重点项目(81873697)

国家自然科学基金-重点项目(81530030)

出版年

2023
中华耳科学杂志
解放军总医院耳鼻咽喉科研究所

中华耳科学杂志

CSTPCDCSCD北大核心
影响因子:0.954
ISSN:1672-2922
被引量1
参考文献量4
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