Sensorineural hearing loss is one of the most common disabling diseases in humans,which is mainly manifested as permanent hearing loss caused by the damage of cochlear hair cells and/or spiral neurons.Ferroptosis is a newly discovered form of regulatory cell death.So far,ferroptosis has been shown to be involved in the pathophysiologi-cal mechanisms of many diseases,such as neurodegenerative diseases,cancer and kidney diseases.At present,relevant studies have reported that ferroptosis may be involved in the development of sensorineural hearing loss.In this paper,the research progress of ferroptosis mechanism is reviewed,and the research status and application prospect of ferropto-sis in sensorineural hearing loss are described,so as to provide new ideas for further research and treatment of sensori-neural hearing loss.
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