首页|良性阵发性位置眩晕女性患者与骨密度及雌二醇关系

良性阵发性位置眩晕女性患者与骨密度及雌二醇关系

Relationship between Benign Paroxysmal Positional Vertigo and Bone Mineral Density and Estradiol in Women

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目的 探讨骨密度和血清雌激素水平与良性阵发性位置性眩晕(benign paroxysmal positional verigo,BP-PV)女性患者不同生理周期间的关系.方法 选取2020年2月至2022年2月宁夏医科大学第二附属医院(银川市第一人民医院)耳鼻咽喉头颈外科收治的BPPV女性患者(病例组)80例及健康女性(对照组)92例,检测两组绝经前期、围绝经期、绝经后期腰椎(L1~L4)骨密度、血清雌二醇水平.结果 病例组不同年龄段骨密度均低于对照组,差异有统计学意义(P<0.05),两组围绝经期、绝经后期骨密度均低于同组绝经前期,差异有统计学意义(P<0.05).病例组不同年龄段血清雌二醇低于对照组,差异有统计学意义(P<0.05),两组围绝经期、绝经后期血清雌二醇水平低于同组绝经前期,差异均有统计学意义(P<0.05).结论 围绝经期、绝经后期女性BPPV患者建议检测雌二醇及骨密度,以减少BPPV复发,避免骨质疏松.
Objective To investigate the relationship between bone mineral density(BMD),serum estrogen level in different stages of physiological cycle in female patients with benign paroxysmal positional vertigo(BPPV).Methods From February 2020 to February 2022,80 female patients with BPPV(study group)were treated at the Department of Otorhinolaryngology Head and Neck Surgery,Second Affiliated Hospital of Ningxia Medical University/First People's Hospital ofYinchuan,and 92 healthy women(control group)were enrolled to tested of their lumbar vertebrae(L1-L4)bone mineral density and serum estradiol levels in the premenopausal,perimenopausal and postmenopausal ages.Re-sults Bone mineral density in the study group at all ages was lower than in the control group(P<0.05).Bone mineral density in perimenopausal and postmenopausal women in both groups was lower than in premenopausal women(P<0.05).Serum estradiol levels demonstrated just the opposite patterns(P<0.05).Conclusion Estradiol levels and bone mineral density should be tested in perimenopausal and postmenopausal women with BPPV to reduce the recurrence of BPPV and avoid osteoporosis.

benign paroxysmal positional vertigobone mineral densityestradiol

李永春、张亚琴、刘翠翠、赵玉桐、申学良、冯宁宇、马小琴、马瑞霞

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宁夏医科大学第二附属医院(银川市第一人民医院)耳鼻咽喉头颈外科(银川 750001)

宁夏回族自治区人民医院功能科

良性阵发性位置性眩晕 骨密度 雌二醇

宁夏回族自治区重点研发计划项目

2020BEG03007

2024

中华耳科学杂志
解放军总医院耳鼻咽喉科研究所

中华耳科学杂志

CSTPCD北大核心
影响因子:0.954
ISSN:1672-2922
年,卷(期):2024.22(3)