Objective To report clinical features and treatment of adult spontaneous cerebrospinal fluid otorrhea.Methods Clinical data of 4 patients suffering from spontaneous cerebrospinal fluid otorrhea surgically treated in our de-partment between June 2015 and June 2022 were retrospectively analyzed.All 4 cases were misdiagnosed as secretory otitis media.Defects were located to the tegmen mastoideum in cases 1 and 3,and to the tegmen tympani in cases 4,all surgically repaired through the transmastoid approach.Defect was located in the tegmen tympani in case 2 with brain tis-sue prolapsed to the tympanum,partly wrapping the ossicles and repaired by mastoidectomy plus adipose tissue pack-ing.Results Satisfactory results were achieved after primary repair in cases 1 and 3.Otorrhea initially persisted after pri-mary repair in case 4 but resolved with conservative treatments.No recurrence occurred during followed ups(6 months to 7 years and 6 months,average=4 years and 3 months).Conclusion Pre-operative temporal bone HRCT and MRI scans for diagnosis are important to ensure accurate location of leakage site and appropriate surgical planning.
cerebral spinal fluid otorrheaspontaneousdefect of the skull basetherapy