Plasma medicine,as an interdisciplinary research field of plasma physics and chemistry,life sciences and clinical medicine,etc.,has received widespread attention from researchers in different research fields and has obtained dramatic development in this century.In this article,based on a brief introduction of the characteristics of cold atmospheric plasmas(CAP),the CAP action mechanisms on tumors,clinical translation challenges,similarities and differences between CAP cancer therapy and radiotherapy,and the synergistic effects of CAP and radiation on the tumors were reviewed.Finally,some possible clinical application scenarios and their feasibilities of the combined CAP-radiation therapy for tumors were discussed.
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