Objective To explore the influence of left and right eyes and different refractive states on the variation of parameters by analyzing the difference and correlation of the diopters before and after ciliary muscle paralysis in civil flying cadets.Methods The observational study was used.The diopters tested by computer optometry before and after ciliary palsy,including degree sphere(DS),degree cylinder(DC)and spherical equivalent(SE),were collected from 2 567 flying cadets in Sichuan area of Civil Aviation Flight University of China from 2017 to 2021.They were grouped into 5 groups by myopia degree:high myopia[-7.000 D,-6.125 D],moderate myopia[-6.000 D,-3.125 D],mild myopia[-3.000 D,-0.125 D],emmetropia[0.000 D]and mild hyperopia[+0.125 D,+3.000 D]by refractive states.The differences of DS,DC,SE in left and right eyes and different refractive states before and after ciliary muscle paralysis were compared.Paired Wilcoxon rank sum test was used for analysing the diopter difference before and after ciliary muscle paralysis,and Spearman correlation coefficient was used for analysing the correlation.Mann-whitney U test and Kruskal-Wallis H test were respectively used to determine the influence of left and right eyes and different refractive states on the changes of diopter before and after ciliary muscle paralysis.Results After ciliary palsy,DS and SE had significant hyperopia drift compared with those before ciliary palsy with statistically significant differences(Z=-35.95,-36.05,both P<0.001).The changes of DS,DC and SE were not affected by eye gender(all P>0.05).The changes of DS and SE were affected by the refractive states(Hc=217.33,237.59,both P<0.001);The change of DC was not affected by the refractive states(Hc=8.22,P=0.084).The changes of DS and SE before and after ciliary palsy were mainly negative,within the range of(-0.525~0.075)D.The higher the degrees of myopia,the more obvious SE hyperopia drift.The correlation of SE values before and after cycloplegia was high(rs=0.870-0.877).The SE correlation was the weakest in the people with high myopia(rs= 0.288),but the strongest for mild myopia(rs=0.767).Conclusions The computerized optometry can be used in large-scale initial screening examination of recruitment physical examination and the measured column diopter value can be used as a reference.