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木丹颗粒治疗糖尿病周围神经病变的临床疗效观察

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目的 分析木丹颗粒对糖尿病周围神经病变(DPN)患者的临床疗效。方法 选择2020年5月—2023年4月在本院治疗的DPN患者50例为研究对象,并按随机分组法分成对照组和试验组,每组25例。其中,对照组采用甲钴胺治疗,试验组在对照组的基础上增加木丹颗粒治疗,两组治疗周期相同,对比相关临床指标。结果 试验组的总有效率高于对照组,对比差异有统计学意义(P<0。05)。治疗前,两组患者SF-36评分、甘油三酯水平以及右正中神经、腓总神经的感觉和运动传导速度比较差异不显著(P>0。05);治疗后,试验组的SF-36评分高于对照组,甘油三酯水平低于对照组,右正中神经、腓总神经的感觉和运动传导速度高于对照组,对比差异有统计学意义(P<0。05)。试验组的肢端感觉异常、麻木、疼痛消失时间均短于对照组,对比差异有统计学意义(P<0。05)。结论 利用木丹颗粒治疗DPN有良好的疗效,可以提高患者生活质量水平,改善神经传导速度,有助于患者恢复,值得临床推广应用。
Clinical Efficacy of Mudan Granules in Treating Diabetic Peripheral Neuropathy
Objective To analyze the clinical efficacy of Mudan granules in the treatment of diabetic peripheral neuropathy(DPN).Methods Fifty cases of DPN patients treated in our hospital during 2020.05-2023.04 were randomly divided into control group and experimental group.The control group was treated with mecobalamine,and the experimental group was supplemented with mudan granules.The treatment period of the two groups was the same,and the relevant clinical indexes were compared.Results The total effective rate of experimental group was higher than that of control group(P<0.05);Before treatment,two groups of patients with SF-36 There were no significant differences in SF-36 score,triglyceride level and sensory and motor conduction velocity of right median nerve and common peroneal nerve(P>0.05).After treatment,SF-36 score of experimental group was higher than control group,triglyceride level was lower than control group,and sensory and motor conduction velocity of right median nerve and common peroneal nerve were higher than control group,all(P<0.05).The disappearance time of acroparesthesia,numbness and pain in experimental group was shorter than that in control group(P<0.05).Conclusion The use of Mudan granules in the treatment of DPN has a good effect,can improve the quality of life,improve nerve conduction speed,and contribute to the recovery of symptoms,worthy of clinical application.

Mudan GranuleDiabetic peripheral neuropathyCurative effect

王亚伟

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江苏省连云港市赣榆区中医院 老年病内分泌科,江苏 连云港 222100

木丹颗粒 糖尿病周围神经病变 疗效

2024

智慧健康

智慧健康

ISSN:
年,卷(期):2024.10(1)
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