Objective To investigate effect of antimicrobial intervention on coagulation function and maternal and infant outcomes of group B streptococcal infection at late pregnancy.Methods The paper chose 66 patients with group B streptococcal infection at late pregnancy admitted to our hospital from January 2019 to November 2020 as study subjects,and divided them into control group and observation group,with 33 cases in each group.Control group was treated with compound sodium chloride,while observation group with penicillin sodium after fetal membrane rupture or labor.Coagulation function and maternal and infant outcomes were observed between two groups.Results After treatment,plasma coagulation time(PT),international standardized ratio(INR),and activated partial thromboplastin time(APTT)in observation group was significantly higher than control group,fibrinogen(FIB)index was significantly lower than control group(P<0.05).Pregnancy outcomes including cesarean section and fetal distress in observation group were significantly lower than control group(P<0.05).Observation group had fewer cases of upper respiratory tract infections than control group,data difference was significant(P<0.05).Conclusion Antibiotics can significantly improve coagulation function,achieve good maternal and infant outcomes,and have significant clinical application effect for patients with Group B streptococcal infection at late pregnancy.
关键词
抗菌药物/B族链球菌感染妊娠晚期/凝血功能/母婴结局
Key words
Antibiotics/Group B streptococcal infection at late pregnancy/Coagulation function/Maternal and infant outcomes
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