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重症肌无力的发病机制及临床治疗研究新进展

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重症肌无力是一种神经肌肉接头传递功能障碍的获得性自身免疫性疾病,80%以上的重症肌无力患者存在胸腺异常。主要临床表现为疲劳后加重的肌无力症状,多数患者于晨起或下午发病,晨轻暮重,活动后症状加重。可伴发吞咽困难、说话不清、饮水呛咳、呼吸困难等,大大降低了患者的生存质量。本文对重症肌无力的发病机制进行分析,并探讨了对重症肌无力的临床治疗方法,目的在于全面而真实地了解不同疗法的效果及副作用,通过真实的综合结论为重症肌无力的治疗提供依据。
New Progress in Pathogenesis and Clinical Treatment of Myasthenia Gravis
Myasthenia gravis is an autoimmune disease that affects neuromuscular junction,and over 80%of myasthenia gravis patients have thymic abnormalities.Main clinical manifestation is muscle weakness symptoms worsening after fatigue.Most patients develop symptoms in the morning or afternoon,being mild in the morning and severe in the evening,and symptoms worsen after physical activity.It can be accompanied by swallowing difficulty,unclear speech,coughing when drinking,and breathing difficulty,which reduces life quality of patients greatly.The paper analysed pathogenesis of myasthenia gravis and explored clinical treatment methods of myasthenia gravis,to understand effect and side effect of different therapies comprehensively and truthfully,and provide basis for treatment of myasthenia gravis based on authentic comprehensive conclusions.

Myasthenia gravisPathogenesisTreatmentProgressSummary

曹文宇、樊兴娟

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南通大学附属医院,江苏 南通 226001

重症肌无力 发病机制 治疗 进展 综述

2024

智慧健康

智慧健康

ISSN:
年,卷(期):2024.10(3)
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