Clinical Application Value Analysis of Glycosylated Hemoglobin in Diagnosis of Diabetes
Objective To explore clinical value of glycosylated hemoglobin(HbA1c)in diagnosis of diabetes.Methods The paper chose 900 patients with diabetes from January 2020 to December 2020 in our hospital as study subjects in observation group,and 900 healthy individuals for physical examination during the same period as control group.All subjects were measured with blood glucose and HbA1c,changes in blood glucose and HbA1c measurements were compared and observed between two groups.At the same time,sensitivity and specificity of fasting blood glucose(FBG),2h postprandial blood glucose(2hPBG)and HbA1c was calculated to detect diabetes.Results Levels of HbA1c,FBG,and 2-hour PBG indicators in observation group were higher than control group,difference was statistically significant(P＜0.05).The first FBG and 2-hour PBG index levels in observation group were statistically significant compared with the second detection level(P＜0.05).There was no statistically significant difference in HbA1c index level compared with the secondary detection,(P＞0.05).Sensitivity and specificity of FBG in diagnosis of diabetes was 98.00%and 80.56%respectively.Sensitivity and specificity of 2hPBG in diagnosis of diabetes was 97.67%and 89.89%respectively.Sensitivity and specificity of HbA1c in diagnosis of diabetes was 98.44%and 97.67%respectively.Conclusion Levels of HbA1c,FBG and 2hPBG of diabetes patients are significantly higher than healthy people,detection of FBG and 2hPBG at different times varies greatly,and HbA1c is relatively more stable.Diagnosis of diabetes with HbA1c is reliable,can obtain high specificity,and reduce incidence of missed diagnosis significantly.
Glycated hemoglobinDiabetesBlood glucose indicatorsDiagnosis of diabetes
NETL
NSTL
万方数据
