Effect of Piperacillin Tazobactam on CRP and PCT Levels of COPD Complicated with Lower Respiratory Tract Infections
Objective To explore effect of piperacillin tazobactam in treatment of chronic obstructive pulmonary disease(COPD)with lower respiratory tract infections.Methods The paper chose 60 COPD patients with lower respiratory tract infections admitted to Suzhou City Wuzhong People's Hospital from August 2020 to May 2023 as study subjects,and divided them into control group and observation group with single pair method,with 30 cases per group.Control group was treated with ceftazidime,while observation group with piperacillin tazobactam.After 14 days of continuous treatment,total treatment effectiveness,inflammatory factor indicators,respiratory distress and health status,lung function indicators,and incidence of adverse reactions were compared between two groups.Results Total effective rate and lung function indicators(FEV1,FVC,FEV1/FVC)of observation group were higher than control group.Inflammatory factor indicators(CRP,PCT)and mMRC,APACHE Ⅱ scores were lower than control group(P＜0.05).Incidence of adverse reactions between two groups showed good consistency(P＞0.05).Conclusion Piperacillin tazobactam can achieve good effect for COPD patients with lower respiratory tract infections,reduce CRP,PCT and other indicators of patients significantly,improve lung function effectively,which is worthy of wide application and promotion in clinical practice.
万方数据
维普
