首页|重组人干扰素a1b雾化吸入治疗毛细支气管炎的效果分析

重组人干扰素a1b雾化吸入治疗毛细支气管炎的效果分析

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目的 研究毛细支气管炎采用重组人干扰素a1b雾化吸入治疗的价值与效果。方法 本文采用随机数字表法将2022年11月—2023年10月诊治的50例毛细支气管炎患儿进行分组,每组收入患儿25例,参照组实施常规治疗,试验组在常规治疗基础上实施重组人干扰素a1b雾化吸入,统计验证两组患儿肺通气功能、炎症指标、临床症状消失时间、住院时间及临床治疗效果。结果 试验组RR低于参照组,VT及VPEF/VE高于参照组,TNF-α、CRP、IL-6均低于参照组,憋喘、肺啰音、咳嗽等临床症状消失时间及住院时间均短于参照组,临床疗效优于参照组,组间差异有统计学意义(P<0。05)。结论 毛细支气管炎患儿在重组人干扰素a1b作用下能快速改善临床症状,可有效调节肺通气功能,减轻炎症反应,有助于提升临床治疗效果。
Effect Analysis of Recombinant Human Interferon a1b Nebulized Inhalation in Treatment of Bronchiolitis
Objective To study value and effect of recombinant human interferon a1b nebulized inhalation therapy for bronchiolitis.Methods The paper divided 50 children with bronchiolitis from November 2022 and October 2023 with random number table method,with 25 cases in each group.Reference group was treated with routine treatment,while experimental group with nebulized inhalation of recombinant human interferon a1b on the basis of routine treatment.Lung ventilation function,inflammatory indicators,clinical symptom disappearance time,length of stay,and clinical treatment effect were statistically verified between two groups.Results RR of experimental group was lower than reference group,VT and VPEF/VE was higher than reference group,TNF-α,CRP and IL-6 was lower than control group,disappearance time and length of stay of clinical symptoms including wheezing,lung rales,and cough was shorter than control group.Clinical effect was better than control group,P<0.05,indicating statistical difference between data indicators.Conclusion Recombinant human interferon a1b can quickly improve clinical symptoms of children with bronchiolitis,regulate lung ventilation function,reduce inflammatory reactions,and improve clinical curative effect effectively.

Recombinant human interferon a1bNebulization inhalationBronchiolitis

刘笑英、黄庆辉、关江伟

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东莞市万江医院,广东 东莞 523050

重组人干扰素a1b 雾化吸入 毛细支气管炎

2024

智慧健康

智慧健康

ISSN:
年,卷(期):2024.10(4)
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