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探讨对卵巢储备功能采取AMH及AFC计数预测的价值

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目的 探讨对卵巢储备功能采取AMH和AFC计数进行预测的价值。方法 回顾性分析本院2022年1月—2023年6月妇科门诊接诊的90例患者作为研究对象,按照卵巢储备功能的差异分为对照组(卵巢功能正常)和观察组(卵巢功能减退),每组45例,对两组患者的抗缪勒管激素(AMH)、窦卵泡数(AFC)、雌二醇(E2)、促卵泡生成素(FSH)及FSH与促黄体生成素(LH)的比值(FSH/LH)进行对比,并以Logistic二元回归分析对具有统计学差异的指标与卵巢储备功能的相关性进行分析。结果 两组在AMH和AFC指标方面的差异存在统计学意义(P<0。05),对两项指标与卵巢储备功能的相关性进行分析,发现AMH、AFC是影响患者卵巢储备功能的关键指标。ROC分析结果提示AMH、AFC联合进行卵巢储备功能预测时,敏感度为88。90%,特异度为88。89%。结论 AMH和AFC计数在卵巢储备功能早期评估及预测方面具有良好的价值。
Value Exploration of Predicting Ovarian Reserve Function with AMH and AFC Counts
Objective To explore value of predicting ovarian reserve function with AMH and AFC counts.Methods The paper reviewed and analyzed 90 patients in gynecological outpatient department of our hospital from January 2022 to June 2023,and divided them into normal ovarian function group(control group)and ovarian dysfunction group(observation group)according to difference in ovarian reserve function.Levels of anti Mullerian hormone(AMH),antral follicle count(AFC),and estradiol(E2),follicle stimulating hormone(FSH)and ratio of follicle stimulating hormone(FSH)to luteinizing hormone(LH)(FSH/LH)was compared between two groups,and correlation between statistically significant indicators and ovarian reserve function was analyzed with logistic binary regression analysis.Results There was statistically significant difference between two groups in terms of AMH and AFC indicators(P<0.05).Correlation between two indicators and ovarian reserve function was analyzed,AMH and AFC was key indicators affecting ovarian reserve function of patients.ROC analysis results indicated,sensitivity of combined prediction of AMH and AFC for ovarian reserve function was 88.90%and specificity was 88.89%.Conclusion AMH and AFC counts have good value for early assessment and prediction of ovarian reserve function.

Ovarian reserve functionAnti Mullerian hormoneSinus follicle count

邵珑

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娄底市娄星区人民医院,湖南 娄底 471000

卵巢储备功能 抗缪勒管激素 窦卵泡计数

2024

智慧健康

智慧健康

ISSN:
年,卷(期):2024.10(4)
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