首页|自拟活血开窍汤联合奥拉西坦治疗轻中型颅脑损伤的临床观察

自拟活血开窍汤联合奥拉西坦治疗轻中型颅脑损伤的临床观察

扫码查看
目的 探讨自拟活血开窍汤联合奥拉西坦治疗轻中型颅脑损伤的临床疗效。方法 选取2021年6月—2022年6月本院收治的46例轻中型颅脑损伤患者为研究对象。并按照随机分组法分为对照组和观察组,每组23例。其中,对照组予以奥拉西坦注射治疗,观察组予以自拟活血开窍汤+奥拉西坦注射治疗。两组比照指标有:临床指标效果、神经功能缺损评分、精神状态量表得分、日常生活能力评分、两组用药后不良反应。结果 治疗有效率方面,观察组表现更好(P<0。05)。治疗前,组间神经功能缺损评分数据对比无显著差异(P>0。05);治疗后,观察组神经功能缺损评分更低(P<0。05)。治疗前,组间精神状态量表得分数据对比无显著差异(P>0。05);治疗后,观察组精神状态量表得分更高(P<0。05)。治疗前,组间日常生活能力量表得分数据对比无显著差异(P>0。05);治疗后,观察组日常生活能力量表得分更高(P<0。05)。不良反应方面,用药后组间数据无明显差别(P>0。05)。结论 奥拉西坦基础上联合用药自拟活血开窍汤,对轻中型颅脑损伤患者具有显著的应用效果,患者神经功能、日常生活能力等问题均能得到有效缓解,用药后精神状态改善,患者用药不会出现严重不良反应,治疗方案安全性较高。总体而言,该用药方案临床推广应用价值较高。
Clinical Observation on Combination of Self-Made Promoting Blood Circulation and Opening Orifices Decoction in Treatment of Mild to Moderate Traumatic Brain Injury
Objective To explore clinical effect of self-made promoting blood circulation and opening orifices decoction combined with olaxitam in treatment of mild to moderate traumatic brain injury.Methods The paper chose 46 individuals with mild to moderate traumatic brain injury from June 2021 to June 2022 for study,and divided them into control group and observation group randomly.Grouping difference was mainly reflected in medication plan.Control group was treated with olaxitam injection,while observation group with self-made promoting blood circulation and opening orifices decoction+olaxitam injection.Comparison indicators of two groups included:clinical indicator effect,neurological deficit scores,mental state scale scores,daily living ability scores,and adverse reactions after medication.Results Treatment effect of observation group was better(P<0.05).Before treatment,there was no significant difference in scores for neurological deficits between groups(P>0.05).After treatment,neurological deficit scores in observation group were lower(P<0.05).Before treatment,there was no significant difference in mental state scale scores between groups(P>0.05).After treatment,observation group had higher scores on mental state scale(P<0.05).Before treatment,there was no significant difference in daily living ability scale scores between groups(P>0.05).After treatment,observation group had higher scores on daily living ability scale(P<0.05).There was no significant difference in adverse reactions data between groups after medication(P>0.05).Conclusion Combination of olaxetan and self formulated promoting blood circulation and opening orifices decoction can achieve significant curative effect on patients with mild to moderate traumatic brain injury,can alleviate neurological function and daily living ability effectively,improves mental state of patients after medication.The medication may not cause serious adverse reactions,with relative safety.Overall,the medication scheme has high clinical promotion and application value.

Mild to moderate traumatic brain injuryPromoting Blood Circulation and Opening Orifices DecoctionOlaxitamIntegrated treatment of traditional Chinese and Western medicineNeurological functionInflammatory factorsAdverse reactions

唐骥文

展开 >

溧阳市中医医院,江苏 溧阳 213300

轻中型颅脑损伤 活血开窍汤 奥拉西坦 中西医结合治疗 神经功能 炎性因子 不良反应

2024

智慧健康

智慧健康

ISSN:
年,卷(期):2024.10(5)
  • 10