首页|冠脉介入应用于冠心病急性心肌梗死治疗中对患者心室重塑的影响研究

冠脉介入应用于冠心病急性心肌梗死治疗中对患者心室重塑的影响研究

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目的 探讨冠脉介入在冠心病急性心肌梗死(CHD-AMI)治疗中对患者心室重塑的影响。方法 选取2017年5月—2022年11月本院收治的88例CHD-AMI患者为研究对象,将其随机分为对照组和研究组,每组44例。其中,对照组采取常规的静脉溶栓治疗,研究组采取冠脉介入治疗,对比两组疗效及心室重塑情况。结果 治疗前,两组NIHSS评分、BNP水平均值区别不明显(P>0。05);治疗3d和治疗后7d,两组NIHSS评分均有所降低,BNP水平治疗3d均有所升高,研究组治疗7d明显降低,对比可见研究组均优于对照组,组间差异有统计学意义(P<0。05);研究组治疗后CK-MB和CK水平均比对照组明显更高,组间差异有统计学意义(P<0。05);研究组治疗后的LESV、LEDV水平均比对照组更低,LVEF水平则比对照组高,组间差异有统计学意义(P<0。05)。结论 CHD-AMI患者经冠脉介入治疗后,不仅能显著缓解心室重塑情况,还能调节患者BNP以及心肌酶水平,进而改善神经功能,值得推荐。
Effect of Coronary Intervention on Ventricular Remodeling in Patients with Acute Myocardial Infarction in Coronary Heart Disease
Objective To investigate the effect of coronary intervention on ventricular remodeling in patients with acute myocardial infarction(CHD-AMI).Methods 88 CHD-AMI patients admitted to hospital from May 2017 to November 2022 were selected as the study objects.Among them,88 patients were selected and randomly divided into two groups,44 patients in the control group received conventional intravenous thrombolysis therapy and 44 patients in the study group received coronary intervention therapy.The efficacy and ventricular remodeling of the two groups were compared.Results Before treatment,there was no significant difference in NIHSS score and BNP level between the two groups(P>0.05);NIHSS score of both groups decreased after 3d and 7d after treatment,BNP level increased after 3d,and the study group significantly decreased after 7d,which showed that the study group was superior to the control group,P<0.05;After treatment,the levels of CK-MB and CK in the study group were significantly higher than those in the control group,P<0.05;LESV and LEDV levels of the study group after treatment were lower than those of the control group,while LVEF levels were higher than those of the control group(P<0.05).Conclusion Coronary interventional therapy in CHD-AMI patients can not only significantly relieve ventricular remodeling,but also regulate BNP and myocardial enzyme levels,thus improving nerve function,which is worthy of recommendation.

Coronary interventionAcute myocardial infarction of coronary heart diseaseVentricular remodeling

郑俊良、荣惠

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萍矿总医院 心血管内科,江西 萍乡 337000

冠脉介入 冠心病急性心肌梗死 心室重塑

2024

智慧健康

智慧健康

ISSN:
年,卷(期):2024.10(5)
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