首页|柴胡疏肝散加减治疗对肝胃不和型慢性胃炎患者临床效果分析

柴胡疏肝散加减治疗对肝胃不和型慢性胃炎患者临床效果分析

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目的 研究柴胡疏肝散加减治疗肝胃不和型慢性胃炎的临床效果及对生活质量影响。方法 选取2021年8月—2023年5月本院收治的肝胃不和型慢性胃炎患者60例,并按照顺序编码分组法分为对照组和实验组,每组30例。其中对照组采用西药治疗,实验组采用西药+柴胡疏肝散加减治疗。比较两组中医症候积分、生活质量评分(GIQLI)、血清炎症因子水平、治疗有效率、胃黏膜组织病理评分、不良反应的情况。结果 实验组治疗有效率优于对照组,组间差异显著有统计学意义(P<0。05)。治疗后,患者中医症候积分、GIQLI评分、血清炎症因子水平、胃黏膜组织病理评分较治疗前均有积极改善(P<0。05),实验组治疗4周时各中医症候积分、血清CRP、胃黏膜组织病理评分较对照组下降显著,且GIQLI评分高于对照组,差异有统计学意义(P<0。05)。实验组不良反应总发生率为13。33%,对照组为10。00%,组间无统计学差异(P>0。05)。结论 柴胡疏肝散加减治疗肝胃不和型慢性胃炎效果确切,可积极改善患者胃炎中医症候、炎症水平与胃黏膜组织病理情况,降低疾病对生活质量的影响,且治疗安全性较高。
Clinical Effect Analysis of Modified Bupleurum Powder for Relieving Liver-Qi for Patients with Chronic Gastritis of Liver Stomach Disharmony Type
Objective To study clinical effect of modified bupleurum powder for relieving liver-qi in treatment of chronic gastritis with liver stomach disharmony and its effect on life quality.Methods The paper chose 60 patients with chronic gastritis met research requirements from August 2021 to May 2023,and divided into control group(30 cases)and experimental group(30 cases)with sequential coding grouping method.Comparison was carried out between control group(treated with Western medicine)and experimental group(with Western medicine and modified bupleurum powder for relieving liver-qi):Traditional Chinese Medicine syndrome scores;Life quality Scores(GIQLI).Serum inflammatory cytokine levels;Treatment effective rate;Pathological scores of gastric mucosal tissue;Adverse reactions.Results Effective rate of treatment in experimental group was 96.67%,that in control group was 80.00%,with significant difference between groups(P<0.05).After treatment,traditional Chinese medicine syndrome scores,GIQLI scores,serum inflammatory factor level,and gastric mucosal tissue pathological scores were higher than before treatment(P<0.05).At 4 weeks of treatment,experimental group showed significant decrease in traditional Chinese medicine syndrome scores,serum CRP,and gastric mucosal tissue pathological scores than control group,and GIQLI scores were higher than control group,with statistical significance(P<0.05).Total incidence of adverse reactions in experimental group was 13.33%,while that in control group was 10.00%.There was no statistically significant difference between groups(P>0.05).Conclusion Modified bupleurum powder for relieving liver-qi can achieve definite effect for chronic gastritis with liver and stomach disharmony,can reduce effect of the disease on life quality,improve traditional Chinese medicine symptoms,inflammation levels,and pathological conditions of gastric mucosa tissue of gastritis patients,which has relatively high treatment safety.

Modified bupleurum powder for relieving liver-qiLiver and stomach disharmonyChronic gastritisLife quality

何细芝、梁健波、尹巧英

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东莞市寮步医院,广东 东莞 523400

柴胡疏肝散加减 肝胃不和 慢性胃炎 生活质量

2024

智慧健康

智慧健康

ISSN:
年,卷(期):2024.10(6)
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