Effect of Spinal Anesthesia on Cognitive Function and Coagulation Function of Elderly Patients with Lower Limb Fractures
Objective To explore effect of general anesthesia and spinal anesthesia on cognitive function and coagulation function of elderly patients with lower limb fractures.Methods The paper chose 100 elderly patients with lower limb fractures admitted to our hospital from June 2021 to June 2023 as study subjects,and divided them into systemic group(n=50 cases)and spinal canal group(n=50 cases).Systemic group was treated with general anesthesia,while spinal canal group with intraspinal anesthesia.Cognitive function scores and coagulation function indicators were compared at different time points(preoperative,postoperative 1 day,3 days,6 days)and different time points(preoperative,induction,immediate postoperative,24 hours,and 48 hours)between two groups.Results Before surgery,there was no statistically significant difference in MMSE scores between two groups(P>0.05).on the 1st,3rd,and 6th day after surgery,MMSE scores of two groups were lower than before surgery(P<0.05),but MMSE scores of spinal canal group were higher than systemic group(P<0.05).D-D level in whole body group was higher immediately after surgery than before anesthesia(P<0.05).TAT level in spinal canal group was lower than systemic group immediately after surgery(P<0.05).TAT levels between two groups at 24 and 48 hours after surgery were higher than before anesthesia in the same group(P<0.05).FIB levels in spinal canal group after anesthesia induction and immediately after surgery were lower than systemic group before anesthesia and at the same time point(P<0.05).FIB levels in both groups were higher at 24 and 48 hours after surgery than before anesthesia in the same group(P<0.05),FIB levels in spinal canal group were lower than systemic group at 24 and 48 hours after surgery(P<0.05).The vWF levels in spinal canal group after anesthesia induction and immediately after surgery were lower than systemic group before anesthesia and at the same time point(P<0.05).Conclusion Spinal anesthesia can achieve ideal effect for elderly patients with lower limb fractures,can improve MMSE scores,reduce occurrence of cognitive function problems,and improve blood hypercoagulability effectively,which is more suitable for elderly patients with lower limb fractures than general anesthesia.
Elderly patients with lower limb fracturesIntraspinal anesthesiaCognitive functionCoagulation function
万方数据
维普
