智慧健康2024,Vol.10Issue(6) :157-160.DOI:10.19335/j.cnki.2096-1219.2024.06.040

早期使用依洛尤单抗对急性心肌梗死患者心功能的影响

Effect of Early Application of Ilozumab on Cardiac Function of Patients with Acute Myocardial Infarction

胡浩
智慧健康2024,Vol.10Issue(6) :157-160.DOI:10.19335/j.cnki.2096-1219.2024.06.040

早期使用依洛尤单抗对急性心肌梗死患者心功能的影响

Effect of Early Application of Ilozumab on Cardiac Function of Patients with Acute Myocardial Infarction

胡浩1
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作者信息

  • 1. 苏州市相城人民医院 心血管内科,江苏 苏州 215000
  • 折叠

摘要

目的 分析早期使用依洛尤单抗对急性心肌梗死患者心功能的影响.方法 选取2022年6月—2023年6月本院收治的112例急性心肌梗死患者为研究对象,并随机分成观察组和对照组,每组56例.观察组采用依洛尤单抗和他汀进行联合治疗,对照组于发生STEMI和NSTEMI后早期给予他汀治疗,比较两组患者在治疗后的心功能情况、LDL-C及安全性.结果 治疗前,两组患者的心功能指标、LDL-C差异不明显(P>0.05);治疗后,观察组LVEF高于对照组,LVEDD、LVESD、LDL-C水平低于对照组,差异有统计学意义(P<0.05).观察组出现不良反应的概率要低于对照组,差异具有统计学意义(P<0.05).结论 通过早期应用依洛尤单抗促进急性心肌梗死患者的心功能迅速恢复,明显改善患者的心功能,明显提高患者满意率.

Abstract

Objective To analyze effect of early application of ilozumab on cardiac function of patients with acute myocardial infarction.Methods The paper chose 112 patients with acute myocardial infarction from June 2022 to June 2023,and divided them into two groups randomly,with 56 cases in each group.Observation group was treated with combined treatment with ilozumab and statin,while control group with early statin treatment after STEMI and NSTEMI.Cardiac function,LDL-C,and safety between two groups was compared after treatment.Results Before treatment,there was no significant difference in cardiac function indicators and LDL-C between two groups,P>0.05.After treatment,there was improvement,and LVEF in observation group was higher than control group,levels of LVEDD,LVESD,and LDL-C were lower than control group,with statistical significance(P<0.05).Incidence of adverse reactions in observation group was lower than control group,P<0.05,difference was statistically significant.Conclusion Early application of ilozumab can promote rapid recovery of cardiac function of patients with acute myocardial infarction,improve cardiac function,and increase satisfaction degree of patients significantly.

关键词

早期使用/依洛尤单抗/急性心肌梗死患者/心功能影响

Key words

Early application/Iloizumab/Patients with acute myocardial infarction/Effect on cardiac function

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出版年

2024
智慧健康

智慧健康

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