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新型降糖药在2型糖尿病联合治疗中的疗效分析

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目的 分析利拉鲁肽在2型糖尿病联合治疗中的疗效。方法 选取2021年1月—2022年12月本院收治的50例患者作为研究对象,根据治疗方法的不同分为两组,观察组采用利拉鲁肽,对照组采用吡格列酮二甲双胍,比较两组治疗效果。结果 两组治疗前HbA1c、空腹血糖对比,组间差异无统计学意义(P>0。05);经治疗,观察组HbA1c、空腹血糖[(6。52±0。18)%、(6。31±0。46)mmol/L]均低于对照组[(7。02±0。37)%、(6。62±2。27)mmol/L],组间差异有统计学意义(P<0。05)。两组干预前BMI对比,差异无统计学意义(P>0。05);经治疗,观察组BMI(23。39±0。28)kg/m2低于对照组(26。43±0。37)kg/m2,组间差异有统计学意义(P<0。05)。结论 利拉鲁肽这种新型降糖药比起口服吡格列酮二甲双胍能够更好地改善患者血糖指标,有利于减轻患者体重,值得推广。
Effect Analysis of New Hypoglycemic Drugs in Combined Treatment of Type 2 Diabetes
Objective To analyze effect of Liraglutide in combined treatment of type 2 diabetes.Methods The paper chose 50 patients admitted to our hospital between January 2021 and December 2022 as study subjects,and divided them into two groups according to different treatment methods.Observation group was treated with liraglutide,while control group with pioglitazone metformin.Treatment effect between two groups was compared.Results There was no statistically significant difference in HbA1c and fasting blood glucose between two groups before treatment(P>0.05).After treatment,the HbA1c was(6.52±0.18)%and fasting blood glucose was(6.31±0.46)mmol/L in observation group,lower than(7.02±0.37)%and(6.62±2.27)mmol/L in control group,with statistical difference(P<0.05).There was no statistically significant difference in BMI between two groups before intervention(P>0.05).After treatment,BMI of observation group was(23.39±0.28)kg·m2,lower than(26.43±0.37)kg·m2 in control group,with statistical difference(P<0.05).Conclusion New type of hypoglycemic drug Liraglutide can improve blood glucose indicators of patients better than oral pioglitazone and metformin,which is beneficial for reducing weight of patients and is worth promoting.

Type 2 diabetesLiraglutidePioglitazone and metforminHbA1cFasting blood glucoseBMI

李红娟、鲁华

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扬州东方医院 内分泌科,江苏 扬州 225002

泰州市中西医结合医院 内分泌科,江苏 泰州 225306

2型糖尿病 利拉鲁肽 吡格列酮二甲双胍 HbA1c 空腹血糖 BMI

2024

智慧健康

智慧健康

ISSN:
年,卷(期):2024.10(7)
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