首页|气管镜联合肺泡灌洗液NGS检查在肺部感染的早期诊断及治疗中的应用

气管镜联合肺泡灌洗液NGS检查在肺部感染的早期诊断及治疗中的应用

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目的 探讨气管镜联合肺泡灌洗液NGS检查在肺部感染的早期诊断及治疗中的应用。方法 选取2022年1月—2023年6月本院收治的75例肺部感染患者作为研究对象,随机将患者分为对照组与观察组,对照组(37例)采用气管镜检查,观察组(38例)采用气管镜联合肺泡灌洗液NGS检查,比较两种检查方法的诊断准确度,并观察两组患者的临床症状消失时间及炎症因子水平。结果 气管镜联合肺泡灌洗液NGS检测的诊断准确度高于气管镜检测;观察组的发热消失时间、咳嗽消失时间、咯痰消失时间、肺部啰音消失时间、住院时间显著低于对照组(P<0。05)。治疗前,两组的WBC、CRP、PCT水平相比无显著差异(P>0。05);治疗后,观察组患者的WBC、CRP、PCT水平显著低于对照组,差异具有统计学意义(P<0。05)。结论 气管镜联合肺泡灌洗液NGS检测在肺部感染的早期诊断中具有较高的准确度,能够缩短患者的临床症状消失时间和住院时间,并有助于更快速有效地降低炎症因子水平。
Application of Bronchoscopy Combined with Bronchoalveolar Lavage Fluid NGS Examination in Early Diagnosis and Treatment of Pulmonary Infections
Objective To explore application of bronchoscopy combined with bronchoalveolar lavage fluid(NGS)examination in early diagnosis and treatment of pulmonary infections.Methods The paper chose 75 patients with pulmonary infections admitted to our hospital from January 2022 to June 2023 as study subjects,and divided them into control group and observation group randomly.37 cases in control group were treated with bronchoscopy,while 38 cases in observation group with bronchoscopy combined with bronchoalveolar lavage fluid(NGS)examination.Diagnostic accuracy of two examination methods was compared,clinical symptom disappearance time and inflammatory factor levels between two groups were observed.Results Diagnostic accuracy of bronchoscopy combined with NGS detection in bronchoalveolar lavage fluid was 98.67%,higher than bronchoscopy detection;Disappearance time of fever,cough,sputum,lung rales,and hospital stay in observation group was significantly lower than control group.Before treatment,there was no significant difference in WBC,CRP,and PCT levels between two groups.After treatment,the WBC,CRP,and PCT levels in observation group were significantly lower than control group,difference was statistically significant(P<0.05).Conclusion Combination of bronchoscopy and NGS detection in bronchoalveolar lavage fluid can achieve high accuracy in early diagnosis of pulmonary infection,can shorten clinical symptom disappearance time and lenth of stay,and reduce inflammatory factor levels quickly and effectively.

TracheoscopyNGS of alveolar lavage fluidPulmonary infectionEarly diagnosis

毛静、陈国萍

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滨海县人民医院 呼吸与危重医学科,江苏 滨海 224500

气管镜 肺泡灌洗液NGS 肺部感染 早期诊断

2024

智慧健康

智慧健康

ISSN:
年,卷(期):2024.10(7)
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