Application of Galactin-3 in Diagnosis and Treatment of Cardiovascular Diseases of Children
Incidence rate of cardiovascular diseases has been rising with high mortality,which endangers human life and health seriously.Galactin-3 plays various biological roles during process of intercellular interactions in the body,including cell proliferation,apoptosis regulation,inflammatory response,fibrosis,and host defense.Study of galactin-3 has been made significant progress in recent years,whose role in cardiovascular disease has been paid attention to increasingly.Galactin-3,as a cardiac biomarker,has been proved to be an important prognostic tool for adults.However,it has not yet been a biomarker in daily clinical practice of pediatric population.The article reviews application of galactin-3 in diagnosis and treatment of cardiovascular diseases including heart failure,viral myocarditis,Kawasaki disease and arrhythmia.
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